Department of Cardiothoracic and Vascular Surgery, Institute of Clinical Medicine, Aarhus University Hospital, Skejby, Aarhus, Denmark.
J Thorac Cardiovasc Surg. 2011 Sep;142(3):697-703. doi: 10.1016/j.jtcvs.2011.01.022. Epub 2011 Feb 16.
The mitral valve annulus naturally conforms to a saddle shape in systole. This configuration is believed to put the leaflets into a lower-energy equilibrium with the annulus and subvalvular apparatus. Conventional flat annuloplasty rings restrict posterior leaflet motion, which may result in a "monocusp" valve, affecting valvular stress distribution. It is hypothesized that saddle-shaped annuloplasty rings cause less distortion of the physiologic leaflet geometry than do flat rings.
Twelve pigs were studied in an acute setting with 3-dimensional echocardiography and sonomicrometry before and after implantation of rigid flat (n = 5) and saddle-shaped (n = 7) annuloplasty rings. The rings were true sized to the annulus with equal anterior-posterior and commissure-commissure circumferential dimensions. The saddle-shaped rings had an annular height to commissural width ratio of 15%.
Saddle-shaped rings maintained both leaflets operational (P < .01). Flat rings made the posterior leaflet immobile and the anterior leaflet aligned flat along the annulus in systole, effectively resulting in monoleaflet function. The average distance from the papillary muscle tips to the posterior annulus decreased by 2.4 ± 0.4 mm after flat ring implantation (P < .01).
Saddle-shaped annuloplasty rings provide better leaflet coaptation geometry than do flat rings by not hoisting the papillary muscles toward the posterior annulus through the commissural chordae, allowing greater leaflet mobility. This entails a potentially beneficial impact on valvular stress distribution that could affect durability of the repaired valve.
二尖瓣瓣环在收缩期自然呈鞍形。这种形态结构使瓣叶与瓣环及瓣下结构处于低能量平衡状态。传统的平面瓣环成形术限制了后瓣叶的运动,可能导致“单叶瓣”,从而影响瓣膜的应力分布。假设鞍形瓣环成形术对生理瓣叶几何结构的扭曲程度小于平面环成形术。
12 头猪在急性状态下接受三维超声心动图和超声心动描记术检查,在植入刚性平面(n = 5)和鞍形(n = 7)瓣环成形术前和术后进行研究。这些环的尺寸与瓣环完全匹配,前后径和交界周径相等。鞍形环的环形高度与交界宽度比为 15%。
鞍形环保持了两个瓣叶的功能(P <.01)。平面环使后瓣叶不能活动,前瓣叶在收缩期沿瓣环呈平面排列,实际上形成单叶瓣功能。瓣环后缘与乳头肌尖端之间的平均距离在植入平面环后减少了 2.4 ± 0.4mm(P <.01)。
鞍形瓣环成形术通过不通过交界腱索将乳头肌向上提升到瓣环后部,提供了更好的瓣叶对合几何形状,从而使瓣叶具有更大的活动度。这可能对瓣膜的应力分布产生有益影响,从而影响修复瓣膜的耐久性。