Gorman Cardiovascular Research Group, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ann Thorac Surg. 2011 Sep;92(3):797-803. doi: 10.1016/j.athoracsur.2011.04.047. Epub 2011 Jul 30.
The primary goal of surgical mitral repair is the reestablishment of normal leaflet coaptation. Surgical techniques that maintain or restore leaflet geometry promote leaflet coaptation. Recent 3-dimensional (3D) echocardiographic studies have shown that saddle-shaped annuloplasty has a salutary influence on leaflet geometry. Therefore we hypothesized that saddle-shaped annuloplasty would improve leaflet coaptation in cases of repair for flail posterior leaflet segments.
Sixteen patients with flail posterior segment and severe mitral regurgitation had valve repair using standard techniques. Eight patients received saddle-shaped annuloplasty and 8 patients received flat annuloplasty. Real-time 3D transesophageal echocardiography was performed before and after repair. Images were analyzed using custom software to calculate mitral annular area (MAA), septolateral dimension (SLD), intercommissural width (CW), total leaflet area (TLA), and leaflet coaptation area (LCA).
Postrepair MAA (flat, 588.6±26.5 mm2; saddle, 628.0±35.3 mm2; p=0.12) and TLA (flat, 2198.5±151.6 mm2; saddle, 2303.9±183.8 mm2; p=0.67) were similar in both groups. Postrepair LCA was significantly greater in the saddle group than in the flat group (226.8±24.0 mm2 and 154.0±13.0 mm2, respectively; p=0.02).
Real-time 3D echocardiography and novel imaging software provide a powerful tool for analyzing mitral leaflet coaptation. When compared with flat annuloplasty, saddle-shaped annuloplasty improves LCA after mitral valve repair for severe mitral regurgitation secondary to flail posterior leaflet segment. Use of saddle-shaped annuloplasty devices may increase repair durability.
手术二尖瓣修复的主要目标是重建正常的瓣叶对合。维持或恢复瓣叶几何形状的手术技术可促进瓣叶对合。最近的三维(3D)超声心动图研究表明,鞍形瓣环成形术对瓣叶几何形状有有益的影响。因此,我们假设鞍形瓣环成形术将改善瓣叶游离后叶节段修复后的瓣叶对合。
16 例瓣叶游离后叶节段伴严重二尖瓣反流的患者采用标准技术行瓣膜修复。8 例患者接受鞍形瓣环成形术,8 例患者接受平面瓣环成形术。修复前后进行实时 3D 经食管超声心动图检查。使用定制软件分析图像以计算二尖瓣环面积(MAA)、间隔侧尺寸(SLD)、室间隔宽度(CW)、总瓣叶面积(TLA)和瓣叶对合面积(LCA)。
修复后的 MAA(平面组,588.6±26.5 mm2;鞍形组,628.0±35.3 mm2;p=0.12)和 TLA(平面组,2198.5±151.6 mm2;鞍形组,2303.9±183.8 mm2;p=0.67)在两组间相似。鞍形组的修复后 LCA 明显大于平面组(分别为 226.8±24.0 mm2和 154.0±13.0 mm2;p=0.02)。
实时 3D 超声心动图和新型成像软件为分析二尖瓣瓣叶对合提供了有力工具。与平面瓣环成形术相比,鞍形瓣环成形术可改善因瓣叶游离后叶节段所致严重二尖瓣反流患者二尖瓣修复后的 LCA。使用鞍形瓣环成形术装置可能会增加修复的耐久性。