Bone Tumour Unit, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK.
Skeletal Radiol. 2011 Aug;40(8):1085-8. doi: 10.1007/s00256-011-1123-5. Epub 2011 Feb 18.
Soft tissue sarcomas (STS) are rare. Affected patients are at increased risk of developing a second primary malignancy, particularly another primary STS. These rarely affect the extremities, tending to occur in the abdomen, head or neck. We describe a patient with myxofibrosarcoma of the buttock who developed a second primary tumour of the same histological type in the contralateral buttock thirty months after excision. Remarkably, the second tumour was symmetrical and there were no predisposing factors or evidence of metastatic spread. The second tumour was a significant size at presentation with encasement of the sciatic nerve. Awareness of the sarcoma patient's increased risk of developing a second tumour could lead to earlier diagnosis and improved outcome. A review of the literature on multiple soft tissue sarcomas is also presented.
软组织肉瘤（STS）较为罕见。患病患者发生第二原发性恶性肿瘤的风险增加，尤其是另一种原发性 STS。这些肿瘤很少发生在四肢，往往发生在腹部、头部或颈部。我们描述了一位臀部黏液纤维肉瘤患者，在切除 30 个月后，对侧臀部出现了同样组织学类型的第二原发性肿瘤。值得注意的是，第二个肿瘤是对称的，没有诱发因素或转移扩散的证据。第二个肿瘤在出现时已经相当大，坐骨神经被包裹在内。提高对肉瘤患者发生第二肿瘤风险的认识，可以导致更早的诊断和更好的治疗效果。本文还对多发性软组织肉瘤的文献进行了回顾。
