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重要性的吸入器设备满意度在哮喘治疗:真实世界的观察医生观察到的合规性和临床/病人报告的结果。

Importance of inhaler-device satisfaction in asthma treatment: real-world observations of physician-observed compliance and clinical/patient-reported outcomes.

机构信息

Adelphi Mill, Adelphi Real World, Grimshaw Lane, Macclesfield, SK10 5JB, UK.

出版信息

Adv Ther. 2011 Mar;28(3):202-12. doi: 10.1007/s12325-010-0108-4. Epub 2011 Feb 10.

Abstract

INTRODUCTION

It is hypothesized that health and patient-reported outcomes in asthma are positively influenced by the level of patient satisfaction with their inhaler device. This paper uses data from a real-world observational study to investigate the extent of the relationship between inhaler satisfaction and patient compliance, and the influence this has on health and patient-reported outcomes.

METHODS

Data were drawn from the Adelphi Respiratory Disease Specific Programme® (Adelphi, Macclesfield, UK), a cross-sectional study of consulting patients in five European countries undertaken between June and September 2009. A range of clinical and patient-reported outcomes were observed allowing analysis of these and their relationship with patient-reported inhaler satisfaction and patient compliance.

RESULTS

The analysis demonstrates that for the majority of patients the higher the level of satisfaction that the patient reports for their device the more likely the patient is observed to be compliant and to experience better outcomes including quality of life (as measured by EuroQol 5 Dimensions [EQ-5D] utility score, P<0.001), fewer exacerbations (P<0.001), fewer hospital visits (P=0.011), fewer healthcare visits (P=0.001), fewer primary care physician visits (P=0.001), and fewer sleep disturbances (P<0.001).

CONCLUSION

The level of patient satisfaction with their inhaler device is observed to have a positive influence on the treatment goals for asthma through its association with improved compliance.

摘要

简介

人们假设,患者对吸入器设备的满意度会对哮喘的健康状况和患者报告的结果产生积极影响。本文使用真实世界观察性研究的数据,调查了吸入器满意度与患者依从性之间的关系程度,以及这种关系对健康和患者报告结果的影响。

方法

数据来自 Adelphi 呼吸系统疾病特定方案®(Adelphi,英国麦克尔斯菲尔德),这是一项 2009 年 6 月至 9 月在五个欧洲国家进行的针对就诊患者的横断面研究。观察了一系列临床和患者报告的结果,从而分析这些结果及其与患者报告的吸入器满意度和患者依从性之间的关系。

结果

分析表明,对于大多数患者来说,患者对其设备的满意度越高,患者就越有可能被观察到依从性更高,并且体验到更好的结果,包括生活质量(通过 EuroQol 5 维度 [EQ-5D] 效用评分衡量,P<0.001)、更少的恶化(P<0.001)、更少的住院(P=0.011)、更少的医疗就诊(P=0.001)、更少的初级保健医生就诊(P=0.001)和更少的睡眠障碍(P<0.001)。

结论

观察到患者对吸入器设备的满意度与其改善依从性有关,从而对哮喘的治疗目标产生积极影响。

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