Department of Women's and Children's Health, Uppsala university, Uppsala, Sweden.
Acta Paediatr. 2011 Jul;100(7):983-91. doi: 10.1111/j.1651-2227.2011.02218.x. Epub 2011 Mar 30.
To investigate early oculo-motor development in a population-based cohort of very preterm infants.
Early oculo-motor development was prospectively studied by measuring smooth pursuit eye movements at 2 and 4 months corrected age in a population of very preterm infants born in Uppsala County 2004-2007. Eighty-one preterm infants were studied, and 32 healthy term infants constituted the control group.
The study group consisted of infants with a mean gestational age of 28 + 5 weeks. At 2 and 4 months corrected age, infants born very preterm showed lower gain (p < 0.001) and proportion of smooth pursuit eye movements (p < 0.001) compared to the control group. The boys showed higher gain of smooth pursuit eye movements at both 2 and 4 months corrected age, compared to girls.
Oculo-motor development measured by smooth pursuit eye movements is delayed in very preterm infants at 2 and 4 months corrected age. This might be a risk factor or early indicator of later perceptual and behavioural impairment.
研究基于人群的极早产儿眼球运动的早期发育。
在乌普萨拉县 2004-2007 年出生的极早产儿人群中,通过测量校正后 2 个月和 4 个月时的平滑追踪眼球运动,前瞻性地研究了早期眼球运动发育。研究了 81 名早产儿,32 名健康的足月婴儿为对照组。
研究组的平均胎龄为 28+5 周。与对照组相比,极早产儿在校正后 2 个月和 4 个月时的增益(p<0.001)和平滑追踪眼球运动的比例(p<0.001)较低。与女孩相比,男孩在校正后 2 个月和 4 个月时的平滑追踪眼球运动增益更高。
校正后 2 个月和 4 个月时,极早产儿的平滑追踪眼球运动测量的眼球运动发育延迟。这可能是以后感知和行为障碍的风险因素或早期指标。