Khan Muhammad Rehan, Maheshwari Prem Kumar, Ali Syed Asad
Department of Paediatrics, The Aga Khan University Hospital, Karachi.
J Coll Physicians Surg Pak. 2011 Feb;21(2):119-20.
Acute necrotizing encephalopathy of childhood (ANEC) is a rare condition characterized by the presence of multifocal symmetrical brain lesions involving mainly thalami, brainstem, cerebellum and white matter. ANEC is a serious and life threatening complication of simple viral infections. We present a case of a young child who developed this condition with classical clinical and radiological findings consistent with ANEC, secondary to swine flu (H1N1). He needed ventilatory support and had profound motor and intellectual deficit on discharge. We report this case with aim of raising awareness about this fatal complication of swine flu which has become a global health care issue these days.
儿童急性坏死性脑病（ANEC）是一种罕见病症，其特征为多灶性对称性脑损伤，主要累及丘脑、脑干、小脑和白质。ANEC是简单病毒感染的一种严重且危及生命的并发症。我们报告一例幼儿病例，该患儿继发于甲型H1N1流感（猪流感），出现了符合ANEC的典型临床和影像学表现。他需要通气支持，出院时存在严重的运动和智力缺陷。我们报告此病例的目的是提高对猪流感这一致命并发症的认识，如今它已成为一个全球医疗保健问题。
