Abbas Qalab, Jafri Sidra Kaleem, Ishaque Sidra, Jamil Muhammad T
Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
J Pediatr Neurosci. 2017 Apr-Jun;12(2):165-167. doi: 10.4103/jpn.JPN_186_16.
Acute necrotizing encephalopathy of childhood (ANEC) is a rare condition mainly affecting children with a distinct clinico-radiologic pattern. Initially thought to be secondary to respiratory viral infections, there have been more insights to the pathogenesis of ANEC including genetics. We present a case of a girl who developed this condition with classical clinico-radiologic findings of ANEC secondary to severe dengue infection and could not survive. We report this case with the aim to raise awareness about this fatal complication of dengue infection as dengue has become a global health-care problem.
儿童急性坏死性脑病（ANEC）是一种罕见疾病，主要影响儿童，具有独特的临床放射学表现。最初认为它继发于呼吸道病毒感染，现在对ANEC的发病机制有了更多认识，包括遗传学方面。我们报告一例女童，她因严重登革热感染出现了具有ANEC典型临床放射学表现的这种疾病，最终未能存活。我们报告此病例的目的是提高对登革热感染这一致命并发症的认识，因为登革热已成为一个全球医疗保健问题。
