Zhou Xiangmin, Zhang Nan, Shen Yunhe, Burke Dan, Konchada Vamsi, Sweet Robert
Center for Research in Education and Simulation Technologies (CREST), University of Minnesota, Minneapolis, MN, USA.
Stud Health Technol Inform. 2011;163:749-55.
Laser-tissue interaction is a multi-physics phenomenon not yet mathematically describable and computationally predictable. It is a challenge to model the laser-tissue interaction for real time laser Benign Prostatic Hyperplasia (BPH) simulation which requires the laser-tissue interaction model to be computationally efficient and accurate. Under the consideration and enforcement of the thermodynamic first law and treating the laser-tissue interaction as a gray-box, utilizing the sensitivity analysis of some key parameters that will affect the laser intensity on the tissue surface with respect to the tissue vaporization rate, a phenomenological model of laser-tissue interaction is developed. The developed laser-tissue interaction model has been implemented for a laser BPH simulator and achieves real time performance (more than 30 frames per second). The model agrees well with the available experimental data.
激光与组织的相互作用是一种多物理现象，目前尚未能用数学方法描述，也无法通过计算进行预测。对实时激光良性前列腺增生（BPH）模拟而言，建立激光与组织相互作用的模型是一项挑战，这要求激光与组织相互作用模型在计算上既高效又准确。在考虑并遵循热力学第一定律的情况下，将激光与组织的相互作用视为一个灰箱，利用某些关键参数对组织表面激光强度相对于组织汽化率的敏感性分析，建立了一个激光与组织相互作用的唯象模型。所建立的激光与组织相互作用模型已应用于激光BPH模拟器，并实现了实时性能（每秒超过30帧）。该模型与现有的实验数据吻合良好。
