van Swol C F, Verdaasdonk R M, Mooibroek J, Boon T A
Department of Urology, University Hospital Utrecht, The Netherlands.
Prog Clin Biol Res. 1994;386:511-9.
A recent development in the treatment of Benign Prostatic Hyperplasia (BPH) is the use of a side firing fiber device coupled with a Nd:YAG laser. In this study, a numerical and an in-vitro model were developed to calculate and visualize the temperature distribution and the associated tissue necrosis due to irradiation of the prostate with Nd:YAG laser light. Different irradiation modalities were included: a static beam, with the irradiating fiber remaining at one place and a moving beam, with the fiber scanning over the surface at different speeds. Also blood vessels were incorporated in the model and showed to have major influence on the resulting tissue necrosis.
良性前列腺增生（BPH）治疗方面的一项最新进展是使用与钕钇铝石榴石（Nd:YAG）激光耦合的侧向发射光纤装置。在本研究中，建立了一个数值模型和一个体外模型，以计算和可视化由于用Nd:YAG激光照射前列腺而产生的温度分布及相关组织坏死情况。研究纳入了不同的照射方式：静态光束，即照射光纤保持在一个位置；以及移动光束，即光纤以不同速度在表面扫描。此外，模型中还纳入了血管，结果显示血管对最终的组织坏死有重大影响。
