Michaelsen T E, Aase A
Department of Vaccinology, National Institute of Public Health, Oslo, Norway.
Methods Mol Med. 2001;66:331-7. doi: 10.1385/1-59259-148-5:331.
Antibodies can protect against meningococcal infection by at least two mechanisms: complement-dependent serum bactericidal activity (SBA), and/ or opsonophagocytosis (OP), leading to destruction of the bacteria (1-4). Regarding group C meningococci, there seems to be a correlation between SBA activity and protection (1), whereas OP has been less well-studied. This function may have a supplementary or even major role in protection against group B meningococci.
补体依赖血清杀菌活性（SBA）和/或调理吞噬作用（OP），从而导致细菌被破坏（1-4）。关于C群脑膜炎球菌，SBA活性与保护作用之间似乎存在关联（1），而对OP的研究较少。该功能在预防B群脑膜炎球菌感染中可能起补充甚至主要作用。
