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经导管主动脉瓣置入术的临床试验经验。

Clinical trial experience with transcatheter aortic valve insertion.

机构信息

Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, Desk J2-3, 9500 Euclid Avenue, Cleveland, OH, USA.

出版信息

Int J Cardiovasc Imaging. 2011 Dec;27(8):1143-54. doi: 10.1007/s10554-011-9825-2. Epub 2011 Feb 20.

DOI:10.1007/s10554-011-9825-2
PMID:21337022
Abstract

Surgical aortic valve replacement has long been considered the standard of care for patients with severe symptomatic aortic stenosis, however, an aging population with increasing complex comorbidities now represents a growing population of patients that is often considered inoperable for a traditional surgical approach. Transcatheter aortic valve implantation is a developing technology that offers an alternative treatment modality for these very high risk patients. This manuscript will review the currently available clinical trial data with transcatheter aortic valve implantation and offer perspective as to the future of this novel technology.

摘要

外科主动脉瓣置换术长期以来一直被认为是严重症状性主动脉瓣狭窄患者的标准治疗方法,然而,人口老龄化和日益复杂的合并症使越来越多的患者通常被认为不适合传统的手术方法。经导管主动脉瓣植入术是一种新兴的技术,为这些极高风险患者提供了一种替代治疗方式。本文将回顾经导管主动脉瓣植入术的现有临床试验数据,并对这项新技术的未来提供一些看法。

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本文引用的文献

1
The global experience with percutaneous aortic valve replacement.经导管主动脉瓣置换术的全球经验。
JACC Cardiovasc Interv. 2010 Nov;3(11):1103-9. doi: 10.1016/j.jcin.2010.10.001.
2
One year follow-up of the multi-centre European PARTNER transcatheter heart valve study.多中心欧洲 PARTNER 经导管心脏瓣膜研究的一年随访结果。
Eur Heart J. 2011 Jan;32(2):148-57. doi: 10.1093/eurheartj/ehq427. Epub 2010 Nov 12.
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Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery.经导管主动脉瓣植入术治疗不能手术的主动脉瓣狭窄患者。
PLoS One. 2013;8(3):e58729. doi: 10.1371/journal.pone.0058729. Epub 2013 Mar 14.
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Cardiovascular imaging 2011 in the International Journal of Cardiovascular Imaging.《国际心血管影像杂志》2011年心血管成像专刊
Int J Cardiovasc Imaging. 2012 Mar;28(3):439-51. doi: 10.1007/s10554-012-0040-6.
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Safety and efficacy of the subclavian approach for transcatheter aortic valve implantation with the CoreValve revalving system.经导管主动脉瓣植入术应用 CoreValve 再修复系统行锁骨下入路的安全性和有效性。
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6
Thirty-day results of the SAPIEN aortic Bioprosthesis European Outcome (SOURCE) Registry: A European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve.SAPIEN 主动脉生物瓣欧洲结果(SOURCE)注册研究的 30 天结果:采用 Edwards SAPIEN 瓣膜行经导管主动脉瓣植入术的欧洲注册研究。
Circulation. 2010 Jul 6;122(1):62-9. doi: 10.1161/CIRCULATIONAHA.109.907402. Epub 2010 Jun 21.
7
Update on transcatheter aortic valve implantation.经导管主动脉瓣植入术的最新进展。
Curr Cardiol Rep. 2010 Sep;12(5):393-403. doi: 10.1007/s11886-010-0126-5.
8
Transapical transcatheter aortic valve implantation: follow-up to 3 years.经心尖入路经导管主动脉瓣植入术:3 年随访结果。
J Thorac Cardiovasc Surg. 2010 May;139(5):1107-13, 1113.e1. doi: 10.1016/j.jtcvs.2009.10.056.
9
Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience.经导管主动脉瓣植入术治疗超高危或手术禁忌的重度症状性主动脉瓣狭窄患者:多中心加拿大经验的急性和晚期结果。
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Transcatheter aortic valve implantation.经导管主动脉瓣植入术
Curr Treat Options Cardiovasc Med. 2009 Dec;11(6):467-75. doi: 10.1007/s11936-009-0049-x.