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经导管主动脉瓣置入术的临床试验经验。

Clinical trial experience with transcatheter aortic valve insertion.

机构信息

Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, Desk J2-3, 9500 Euclid Avenue, Cleveland, OH, USA.

出版信息

Int J Cardiovasc Imaging. 2011 Dec;27(8):1143-54. doi: 10.1007/s10554-011-9825-2. Epub 2011 Feb 20.

Abstract

Surgical aortic valve replacement has long been considered the standard of care for patients with severe symptomatic aortic stenosis, however, an aging population with increasing complex comorbidities now represents a growing population of patients that is often considered inoperable for a traditional surgical approach. Transcatheter aortic valve implantation is a developing technology that offers an alternative treatment modality for these very high risk patients. This manuscript will review the currently available clinical trial data with transcatheter aortic valve implantation and offer perspective as to the future of this novel technology.

摘要

外科主动脉瓣置换术长期以来一直被认为是严重症状性主动脉瓣狭窄患者的标准治疗方法,然而,人口老龄化和日益复杂的合并症使越来越多的患者通常被认为不适合传统的手术方法。经导管主动脉瓣植入术是一种新兴的技术,为这些极高风险患者提供了一种替代治疗方式。本文将回顾经导管主动脉瓣植入术的现有临床试验数据,并对这项新技术的未来提供一些看法。

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