Beppu S
Department of Cardiovascular Dynamics, National Cardiovascular Center, Suita.
J Cardiol. 1990;20(4):1009-19.
A deformation of the left ventricular cavity is commonly observed in myocardial infarction, which directly influences the ventricular function. Even in cases without ischemia, a deformation of the left ventricle during systole or diastole is presumed to affect its function. Inward bending of the left ventricular posterobasal wall in giant left atrium is an example of the unfavourable effects of such a deformation. Systolic flattening of the left ventricle is atrial septal defect complicated by pulmonary hypertension is an example of the favourable influences by such a deformation. A regional wall motion abnormality observed in these cases is explained by the deformation attributed to the relationship between the left ventricle and left atrium or between the left and right ventricles. The relationship between the deformation and the function of the left ventricle in ventricular aneurysm can be explained well by the mode of blood turnover within the left ventricle. Contrast studies via the left atrium revealed that blood flow into the left ventricle did not reach the cardiac apex with an aneurysm, but immediately turned upwards towards the outflow tract. These results indicate that, although the left ventricle is anatomically a single cavity, it consists of functioning and non-functioning portions for blood turnover. A morphological abnormality of the left ventricle influences its function even without myocardial ischemia. It is necessary to relate all morphological changes of the left ventricle to cardiac function, regardless of the causes of a deformation.
左心室腔变形在心肌梗死中常见,这直接影响心室功能。即使在无缺血的情况下,左心室在收缩期或舒张期的变形也被认为会影响其功能。巨大左心房时左心室后基底壁的向内弯曲就是这种变形产生不利影响的一个例子。房间隔缺损合并肺动脉高压时左心室的收缩期扁平则是这种变形产生有利影响的一个例子。这些病例中观察到的局部室壁运动异常可通过左心室与左心房之间或左右心室之间关系所导致的变形来解释。室壁瘤中左心室变形与功能之间的关系可通过左心室内的血流模式得到很好的解释。经左心房的造影研究显示,存在室壁瘤时流入左心室的血流无法到达心尖,而是立即向上转向流出道。这些结果表明,尽管左心室在解剖学上是一个单一腔室,但就血流而言它由起作用和不起作用的部分组成。即使没有心肌缺血,左心室的形态异常也会影响其功能。有必要将左心室的所有形态变化与心功能联系起来,而不管变形的原因是什么。