Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Neurol India. 2011 Jan-Feb;59(1):87-91. doi: 10.4103/0028-3886.76876.
Lipomatous meningiomas are an uncommon subtype of meningiomas. In the present report, the clinical characteristics, neuroimaing and pathological features of 5 patients (4 males, 1 female; age range, 17-45 years; mean age, 35.2 years) with lipomatous meningioma were analyzed. The neuro-pathological reevaluation of lipomatous meningioma involved assessment of histological features proposed by the current WHO classification. The presence or absence of high whorls, fascicles, solid growth, glial invasion, necrosis and nuclear pleomorphism was assessed. The most common presenting symptom was seizures. Location of tumor was frontal (3 cases), parietal (1 case) and fronto-temporal (1 case). All cases showed radiological features of conventional meningioma. Complete excision of tumor along with involved dura was performed in all the patients. Three tumors were meningothelial and 2 were transitional. Tumoral lipid content was variable from 10% to 30%. In addition, there were microcystic features (2 cases) and psammoma bodies (1 case). No recurrence was noted in any of our cases till the last follow-up. Lipomatous meningioma represents a rare distinctive type of meningioma, with a good prognosis with complete removal.
脂肪化生型脑膜瘤是脑膜瘤的一种不常见亚型。本报告分析了 5 例（男 4 例，女 1 例；年龄 17-45 岁，平均 35.2 岁）脂肪化生型脑膜瘤患者的临床特征、神经影像学和病理学特征。脂肪化生型脑膜瘤的神经病理学重新评估包括评估当前世界卫生组织分类提出的组织学特征。评估有无高嵴、束状、实性生长、胶质浸润、坏死和核多形性。最常见的首发症状是癫痫。肿瘤部位为额部（3 例）、顶叶（1 例）和额颞部（1 例）。所有病例均显示出常规脑膜瘤的影像学特征。所有患者均行肿瘤及受累硬脑膜的完全切除术。3 例为脑膜上皮型，2 例为过渡型。肿瘤脂质含量从 10%到 30%不等。此外，有 2 例存在微囊特征，1 例存在砂粒体。在最后一次随访时，我们所有的病例均无复发。脂肪化生型脑膜瘤是一种罕见的独特脑膜瘤类型，完全切除后预后良好。
