Nemetz Marcos Antonio, Thomazelli Fúlvio Clemo Santos, Granero Luzete Cristina Silva, Nemetz Ana Beduschi, Dos Santos Marcela Bonalumi
Universidade Federal do Rio Grande do Sul - UFRGS, Médico Endocrinologista. Professor da Disciplina de Endocrinologia do Curso de Medicina da Fundação Universidade Regional de Blumenau, Brazil.
Braz J Otorhinolaryngol. 2011 Jan-Feb;77(1):77-83. doi: 10.1590/s1808-86942011000100013.
The association between differentiated thyroid carcinoma (DTC) and chronic lymphocytic thyroiditis (CLT) has been reported in literature. To evaluate the incidence of this association and to determine whether the CLT may influence on the early initial staging of DTC when associated with other variable risks. Historical (retrospective) cohort. Fifty two patients with DTC were evaluated from 1999 to 2009. They were divided into two groups. The first group had 35 patients with DTC without DLT; the second had 17 patients with CLT. Total thyroidectomy was the treatment chosen for all patients. Similarities shared in both groups such as age, gender, histological tumor type, tumor diameter, regional only or with distant metastases, extrathyroidal invasion, multifocality and presence of tumor capsule were considered. T-Student tests and Chi-square tests were applied to analyze the data. The incidence of DTC without CLT was higher that of DTC+CLT (p=0.0126). We noticed no statistic differences between the common variables analyzed. CLT occurred in 33% of the patients with DCT. All cases of DTC were in the early stages.
文献中已报道了分化型甲状腺癌（DTC）与慢性淋巴细胞性甲状腺炎（CLT）之间的关联。为评估这种关联的发生率，并确定CLT与其他可变风险相关时是否会影响DTC的早期初始分期。采用历史性（回顾性）队列研究。对1999年至2009年期间的52例DTC患者进行了评估。他们被分为两组。第一组有35例无DLT的DTC患者；第二组有17例CLT患者。所有患者均选择全甲状腺切除术。考虑了两组共有的相似因素，如年龄、性别、肿瘤组织学类型、肿瘤直径、仅区域转移或伴有远处转移、甲状腺外侵犯、多灶性以及肿瘤包膜的存在情况。应用t检验和卡方检验分析数据。无CLT的DTC发生率高于DTC + CLT（p = 0.0126）。我们注意到所分析的常见变量之间无统计学差异。CLT发生在33%的DCT患者中。所有DTC病例均处于早期阶段。
