Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443 Bialystok, Poland.
Cell Biochem Biophys. 2011 Sep;61(1):145-55. doi: 10.1007/s12013-011-9171-y.
Bilayer lipid membranes composed of phosphatidylcholine and decanoic acid or phosphatidylcholine and decylamine were investigated using electrochemical impedance spectroscopy. Interaction between membrane components causes significant deviations from the additivity rule. Area, capacitance, and stability constant values for the complexes were calculated based on the model assuming 1:1 stoichiometry, and the model was validated by comparison of these values to experimental results. We established that phosphatidylcholine and decylamine form highly stable 1:1 complexes. In the case of decanoic acid-modified phosphatidylcholine membranes, complexes with stoichiometries other than 1:1 should be taken into consideration.
双层类脂膜由磷脂酰胆碱和癸酸或磷脂酰胆碱和癸胺组成，采用电化学阻抗谱进行了研究。膜成分之间的相互作用导致显著偏离加和规则。根据假定 1:1 化学计量比的模型计算了复合物的面积、电容和稳定常数值，并通过将这些值与实验结果进行比较来验证模型。我们确定磷脂酰胆碱和癸胺形成高度稳定的 1:1 配合物。对于癸酸修饰的磷脂酰胆碱膜，应考虑其他化学计量比的复合物。
Zotero 插件
