Khan Arif O
Pediatric Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Ophthalmic Genet. 2011 Sep;32(3):129-37. doi: 10.3109/13816810.2010.544363. Epub 2011 Feb 22.
Primary congenital glaucoma (isolated goniodysgenesis) has classic phenotypic features such as increased measured intraocular pressure, globe enlargement (buphthalmos) with associated myopia, Descemet membrane tears, corneal haze/scarring with associated astigmatism, iris atrophy, and optic nerve cupping. These signs also occur in developmental glaucoma (anterior segment dysgeneses) with infantile onset. However, similar findings can occur in other pediatric conditions which are sometimes are mistaken as early childhood glaucoma.
原发性先天性青光眼(孤立性前房角发育异常)具有典型的表型特征,如测量眼压升高、眼球增大(牛眼)伴近视、Descemet 膜破裂、角膜混浊/瘢痕伴散光、虹膜萎缩和视神经杯状凹陷。这些体征也见于婴儿期发病的发育性青光眼(前段发育异常)。然而,类似的表现也可能出现在其他儿科疾病中,这些疾病有时会被误诊为幼儿青光眼。