[儿童慢性咳嗽的病因：111例分析]

[Causes of chronic cough in children: an analysis of 111 cases].

作者信息

Zhang Xiao-Bo, Nong Guang-Min

机构信息

Department of Pediatrics, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2011 Feb;13(2):131-4.

PMID:21342623

Abstract

OBJECTIVE

To investigate the causes of chronic cough in children.

METHODS

A prospective cohort study was performed on 111 children with chronic cough who were referred to the First Affiliated Hospital of Guangxi Medical University between December 2008 and January 2011. The causes of chronic cough were investigted.

RESULTS

Cough variant asthma (45 cases, 40.5%) was the most common cause of chronic cough, followed by upper airway cough syndrome (34 cases, 30.6%), postinfectious cough (19 cases, 17.1%), allergic cough (5 cases, 4.5%), Tourette's syndrome (4 cases, 3.6%), psychogenic cough (1 case, 0.9%) and endobronchial tuberculosis (1 case, 0.9%). The causes were not identified in 2 cases (1.8%). A single cause for chronic cough was noted in 60 patients (54.1%), and multiple potential causes were noted in 49 patients (44.1%), including two coexisting causes in 47 patients (42.3%) and three in 2 patients (1.8%).

CONCLUSIONS

The top three causes of chronic cough in children are cough variant asthma, upper airway cough syndrome and postinfectious cough.

摘要

目的

探讨儿童慢性咳嗽的病因。

方法

对2008年12月至2011年1月转诊至广西医科大学第一附属医院的111例慢性咳嗽儿童进行前瞻性队列研究，调查慢性咳嗽的病因。

结果

咳嗽变异性哮喘（45例，40.5%）是慢性咳嗽最常见的病因，其次是上气道咳嗽综合征（34例，30.6%）、感染后咳嗽（19例，17.1%）、过敏性咳嗽（5例，4.5%）、抽动秽语综合征（4例，3.6%）、心因性咳嗽（1例，0.9%）和支气管内膜结核（1例，0.9%）。2例（1.8%）病因未明确。60例患者（54.1%）为单一慢性咳嗽病因，49例患者（44.1%）存在多种潜在病因，其中47例患者（42.3%）有两种并存病因，2例患者（1.8%）有三种并存病因。