Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA.
Clin Infect Dis. 2011 Jan 1;52 Suppl 1:S60-8. doi: 10.1093/cid/ciq022.
During the spring of 2009, pandemic influenza A (H1N1) virus (pH1N1) was recognized and rapidly spread worldwide. To describe the geographic distribution and patient characteristics of pH1N1-associated deaths in the United States, the Centers for Disease Control and Prevention requested information from health departments on all laboratory-confirmed pH1N1 deaths reported from 17 April through 23 July 2009. Data were collected using medical charts, medical examiner reports, and death certificates. A total of 377 pH1N1-associated deaths were identified, for a mortality rate of .12 deaths per 100,000 population. Activity was geographically localized, with the highest mortality rates in Hawaii, New York, and Utah. Seventy-six percent of deaths occurred in persons aged 18-65 years, and 9% occurred in persons aged ≥ 65 years. Underlying medical conditions were reported for 78% of deaths: chronic lung disease among adults (39%) and neurologic disease among children (54%). Overall mortality associated with pH1N1 was low; however, the majority of deaths occurred in persons aged <65 years with underlying medical conditions.
2009 年春季，甲型 H1N1 流感（pH1N1）病毒被发现并迅速在全球范围内传播。为了描述美国与 pH1N1 相关的死亡病例的地理分布和患者特征，疾病预防控制中心向各州卫生部门请求了自 2009 年 4 月 17 日至 7 月 23 日期间报告的所有经实验室确认的 pH1N1 死亡病例的信息。数据通过病历、法医报告和死亡证明收集。共发现 377 例与 pH1N1 相关的死亡病例，死亡率为每 10 万人中有 0.12 人死亡。活动具有地域局限性，夏威夷、纽约和犹他州的死亡率最高。76%的死亡发生在 18-65 岁的人群中，9%的死亡发生在≥65 岁的人群中。78%的死亡病例有基础疾病报告：成年人的慢性肺病（39%）和儿童的神经疾病（54%）。总体而言，pH1N1 相关的死亡率较低；然而，大多数死亡发生在有基础疾病的<65 岁人群中。
