Department of Biomedical Materials Science, The University of Mississippi Medical Center, Jackson, MS 39216, USA.
J Biomater Appl. 2012 Jul;27(1):55-65. doi: 10.1177/0885328210394471. Epub 2011 Feb 22.
Acetabular hip joint components manufactured from gamma-sterilized ultra high molecular weight polyethylene (UHMWPE), gamma cross-linked UHMWPE, or polycarbonate-urethane (PCU) polymers were evaluated in a hip joint simulator, using cobalt alloy femoral components, for at least 5 million cycles. The volume of material losses due to wear was calculated for each type of sample, based upon mass loss measurements, every 500,000 cycles. The loss of material for the conventional UHMWPE was much higher than for the cross-linked UHMWPE, showing about a 70% reduction in wear due to cross-linking. The material loss for the PCU samples appears to have been at least 24% lower than for the cross-linked UHMWPE. Based upon these results, the PCU material seems to have potential for use as an alternative bearing material to UHMWPE for total hip replacement surgeries.
采用钴合金股骨部件，在髋关节模拟器中对经伽马射线灭菌的超高分子量聚乙烯（UHMWPE）、伽马射线交联 UHMWPE 或聚碳酸酯-聚氨酯（PCU）聚合物制造的髋臼髋关节部件进行了评估，经过至少 500 万次循环。基于质量损失测量值，每 50 万次循环计算每种类型样品的磨损导致的材料损失量。与交联 UHMWPE 相比，传统 UHMWPE 的材料损失要高得多，交联导致磨损减少了约 70%。PCU 样品的材料损失似乎至少比交联 UHMWPE 低 24%。根据这些结果，PCU 材料似乎有可能替代全髋关节置换手术中的 UHMWPE 作为一种替代的轴承材料。
