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Drug-related Sleep Stage Changes: Functional Significance and Clinical Relevance.

作者信息

Roehrs Timothy, Roth Thomas

机构信息

Director of Research, Sleep Disorders & Research Center, Henry Ford Health System and Professor, Department of Psychiatry and Behavioral Neuroscience, Wayne State University, School of Medicine, Detroit, MI.

出版信息

Sleep Med Clin. 2010 Dec 1;5(4):559-570. doi: 10.1016/j.jsmc.2010.08.002.

DOI:10.1016/j.jsmc.2010.08.002
PMID:21344068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3041980/
Abstract
摘要

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Nelotanserin, a novel selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia.奈洛替坦，一种新型选择性人类 5-羟色胺 2A 反向激动剂，用于治疗失眠。
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EEG spectral analysis in primary insomnia: NREM period effects and sex differences.原发性失眠的脑电图频谱分析：非快速眼动期效应与性别差异
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Effect of gaboxadol on sleep in adult and elderly patients with primary insomnia: results from two randomized, placebo-controlled, 30-night polysomnography studies.加波沙朵对成年和老年原发性失眠患者睡眠的影响：两项为期30晚的随机、安慰剂对照多导睡眠图研究结果
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Slow wave sleep enhancement with gaboxadol reduces daytime sleepiness during sleep restriction.加波沙朵增强慢波睡眠可减轻睡眠限制期间的日间嗜睡。
Sleep. 2008 May;31(5):659-72. doi: 10.1093/sleep/31.5.659.
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Behavioral and physiological consequences of sleep restriction.睡眠限制的行为和生理后果。
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Efficacy of the selective extrasynaptic GABA A agonist, gaboxadol, in a model of transient insomnia: a randomized, controlled clinical trial.选择性突触外GABAA激动剂加波沙朵在短暂性失眠模型中的疗效：一项随机对照临床试验
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Insufficient non-REM sleep intensity in narcolepsy-cataplexy.发作性睡病-猝倒症中快速眼动睡眠以外睡眠强度不足
Sleep. 2007 Aug;30(8):980-9. doi: 10.1093/sleep/30.8.980.