Zaben Malik J A, Harrisson Stuart E, Mathad N V
Department of Neurosurgery, Wessex Neurological Centre, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, UK.
Br J Neurosurg. 2011 Dec;25(6):754-6. doi: 10.3109/02688697.2010.544791. Epub 2011 Feb 23.
Prolactinomas are common secretory pituitary tumours, usually managed with dopamine agonists. There have previously been case reports of rarer giant prolactinomas causing invasion of surrounding structures. We describe a case report of an exceptionally aggressive giant prolactinoma that eroded the occipital condyles causing cranio-cervical joint instability mandating surgical fixation.
催乳素瘤是常见的分泌性垂体肿瘤，通常采用多巴胺激动剂进行治疗。此前有病例报告称，罕见的巨大催乳素瘤会侵犯周围结构。我们描述了一例极具侵袭性的巨大催乳素瘤病例，该肿瘤侵蚀枕髁，导致颅颈关节不稳，需要进行手术固定。
