Health Protection Agency Centre for Infections, London, UK.
J Public Health (Oxf). 2011 Jun;33(2):197-204. doi: 10.1093/pubmed/fdr011. Epub 2011 Feb 23.
Prisons are important settings for blood-borne virus control because of the high prevalence of hepatitis C and B viral infections (HCV and HBV), and behaviours associated with transmission among prisoners.
Data from sentinel laboratories in England were used to identify testing for hepatitis C (anti-HCV) and hepatitis B [hepatitis B surface antigen (HBsAg) and anti-hepatitis B core antigen (HBc)] among male and female prisoners between 2005 and 2008.
Between 2005 and 2008, 10 723 prisoners from 39 prisons in England were tested for anti-HCV, anti-HBc and/or HBsAg. Overall, 24.2% prisoners tested positive for anti-HCV. Anti-HCV testing increased 47% over 4 years (P < 0.001), whilst the proportion testing positive decreased significantly from 26% in 2005 to 23% in 2008 (χ(2)= 10.0, df = 3, P = 0.030). In total, 13.9% people tested positive for anti-HBc. Of 5151 people tested for anti-HBc, 4433 were also tested for HBsAg; of these 2.4% were HBsAg positive. HBsAg testing increased 35% between 2005 and 2008, with no significant change in the proportion testing positive. Between 2005 and 2008, 2.4% (CI: 2.32-2.43%) of the prison population (24 prisons) were estimated to have been tested for anti-HCV.
Although hepatitis testing has increased, only a small proportion of the prison population were tested. More testing is required to identify infected prisoners and refer them for appropriate treatment.
由于丙型和乙型肝炎病毒(HCV 和 HBV)感染率高,以及囚犯之间传播相关行为,监狱是控制血源性病毒的重要场所。
利用英格兰哨点实验室的数据,对 2005 年至 2008 年间男性和女性囚犯中丙型肝炎(抗-HCV)和乙型肝炎[乙型肝炎表面抗原(HBsAg)和抗乙型肝炎核心抗原(HBc)]检测情况进行了鉴定。
2005 年至 2008 年间,英格兰 39 所监狱的 10723 名囚犯接受了抗-HCV、抗-HBc 和/或 HBsAg 检测。总体而言,24.2%的囚犯抗-HCV 检测呈阳性。4 年来,抗-HCV 检测增加了 47%(P<0.001),而呈阳性的比例从 2005 年的 26%显著下降到 2008 年的 23%(χ(2)=10.0,df=3,P=0.030)。共有 13.9%的人抗-HBc 检测呈阳性。在接受抗-HBc 检测的 5151 人中,有 4433 人同时接受了 HBsAg 检测;其中 2.4%的人 HBsAg 呈阳性。2005 年至 2008 年间,HBsAg 检测增加了 35%,而呈阳性的比例没有明显变化。2005 年至 2008 年间,据估计,有 2.4%(95%置信区间:2.32-2.43%)的监狱人口(24 所监狱)接受了抗-HCV 检测。
尽管肝炎检测有所增加,但只有一小部分监狱人口接受了检测。需要进行更多的检测,以确定感染的囚犯,并将他们转介到适当的治疗机构。