Department of Melanoma/Medical Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Melanoma Res. 2011 Apr;21(2):160-3. doi: 10.1097/CMR.0b013e328344958c.
Treatment of patients with metastatic uveal melanoma is very challenging because the tumor commonly spreads to the liver, surgical resection of metastases is rarely possible, and there is no standard effective systemic therapy. We report the case of a 38-year-old man, who presented with metastatic involvement of the left ventricle as the first site of uveal melanoma recurrence 13 years after treatment of his primary tumor. The metastatic tumor was considered unresectable. We describe the patient's medical management over the next 3 years, the course of his disease, and the results of our review of the literature.
治疗转移性葡萄膜黑色素瘤的患者极具挑战性，因为肿瘤通常会扩散到肝脏，转移灶的手术切除很少可行，也没有标准的有效全身治疗方法。我们报告了一例 38 岁男性患者，在原发性肿瘤治疗 13 年后，首次出现左心室转移性葡萄膜黑色素瘤复发。转移性肿瘤被认为无法切除。我们描述了患者在接下来 3 年中的医疗管理、疾病过程以及我们对文献的回顾结果。
