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小儿附睾炎需要使用抗生素吗?

Are antibiotics necessary for pediatric epididymitis?

作者信息

Santillanes Genevieve, Gausche-Hill Marianne, Lewis Roger J

机构信息

Department of Emergency Medicine, LAC + USC Medical Center, Los Angeles, CA 90033, USA.

出版信息

Pediatr Emerg Care. 2011 Mar;27(3):174-8. doi: 10.1097/PEC.0b013e31820d647a.

Abstract

OBJECTIVES

To determine the percentage of cases of epididymitis in pediatric patients that is of bacterial cause and to identify factors that predict a positive urine culture.

METHODS

We conducted a retrospective chart review of patients diagnosed with acute epididymitis or epididymo-orchitis in 1 pediatric emergency department for 11 years. Charts were reviewed for historical, physical, laboratory, and radiologic data. A positive urine culture was used to identify patients with a bacterial cause of epididymitis.

RESULTS

A total of 160 patient records were initially identified as having a diagnosis of epididymitis; of these, 20 met exclusion criteria or did not have records available for review and 140 cases of epididymitis were reviewed. Patients' age ranged from 2 months to 17 years, with a median age of 11 years. Of these patients, 91% received empiric antibiotic therapy. Also, of these patients, 97 (69%) had a urine culture sent, of whom 4 (4.1%; 95% confidence interval, 1.1%-10.2%) were positive. Of the 4 positive urine cultures, 3 had organisms not sensitive to usual empiric therapy for urinary tract infections. The boys with positive urine cultures were not significantly different from the other patients in age, maximum temperature, or number of white blood cells on urinalysis.

CONCLUSIONS

Given the low incidence of urinary tract infections in boys with epididymitis, in prepubertal patients, antibiotic therapy can be reserved for young infants and those with pyuria or positive urine cultures. Because it is difficult to predict which patients will have a positive urine culture, urine cultures should be sent on all pediatric patients with epididymitis.

摘要

目的

确定小儿附睾炎病例中由细菌引起的比例,并识别预测尿培养阳性的因素。

方法

我们对一家儿科急诊科11年间诊断为急性附睾炎或附睾睾丸炎的患者进行了回顾性病历审查。审查病历以获取病史、体格检查、实验室和放射学数据。尿培养阳性用于识别由细菌引起附睾炎的患者。

结果

最初共识别出160例诊断为附睾炎的患者记录;其中,20例符合排除标准或没有可供审查的记录,对140例附睾炎病例进行了审查。患者年龄从2个月至17岁不等,中位年龄为11岁。这些患者中,91%接受了经验性抗生素治疗。此外,这些患者中,97例(69%)进行了尿培养,其中4例(4.1%;95%置信区间,1.1%-10.2%)为阳性。在4例尿培养阳性病例中,3例的病原体对常见的尿路感染经验性治疗不敏感。尿培养阳性的男孩在年龄、最高体温或尿液分析中的白细胞数量方面与其他患者无显著差异。

结论

鉴于附睾炎男孩尿路感染的发生率较低,对于青春期前患者,抗生素治疗可保留用于小婴儿以及有脓尿或尿培养阳性的患者。由于难以预测哪些患者尿培养会呈阳性,所有患有附睾炎的儿科患者均应进行尿培养。

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