评估抗生素在儿科患者急性附睾炎治疗中的必要性：回顾性研究文献综述和数据分析。

Evaluating the Necessity of Antibiotics in the Treatment of Acute Epididymitis in Pediatric Patients: A Literature Review of Retrospective Studies and Data Analysis.

机构信息

From the Department of Pediatrics, University of South Florida, Tampa, FL.

出版信息

Pediatr Emerg Care. 2021 Dec 1;37(12):e1675-e1680. doi: 10.1097/PEC.0000000000001018.

DOI:10.1097/PEC.0000000000001018

PMID:28099292

Abstract

OBJECTIVES

This literature review and data analysis aims to evaluate the percentage of pediatric patients with acute epididymitis found to have bacterial etiology and the percentage of patients in these studies that were treated with antibiotic therapy versus conservative therapy.

METHODS

A search of EBSCO through January 13, 2016, using the key words epididymitis or epididymo-orchitis and child, children, or pediatric, identified 542 potential studies.Twenty-seven retrospective studies met the inclusion criteria, containing patients aged 21 years or younger with acute epididymitis or epididymoorchitis. The number and age of patients, urine cultures and urinalysis results, number of patients treated with antibiotics, and incidence were extracted.

RESULTS

A total of 1496 patients with acute epididymitis were identified. A urinalysis was obtained for 1124 patients, and 190 (16.9%) were positive. Aurine culturewas obtained for 670 patients, and 100 (14.9%) were positive. Fourteen studies addressed antibiotic administration wherein 652 patients were with acute epididymitis and 554 (85%) received antibiotics.Of 502 patients with urinalysis results, urine culture results, and antibiotic treatment rates, 54 (10.8%) were positive for a bacterial source. Antibiotics were administered to 410 (81.7%) of these 502 patients.

CONCLUSIONS

Practitioners should consider only prescribing antibiotics to patients with acute epididymitis if there is an abnormal urinalysis or urine culture.

摘要

目的

本文献回顾和数据分析旨在评估患有急性附睾炎的儿科患者中发现细菌性病因的比例，以及这些研究中接受抗生素治疗与保守治疗的患者比例。

方法

通过 EBSCO 数据库，于 2016 年 1 月 13 日之前，使用关键词“epididymitis 或 epididymo-orchitis 和 child、children 或 pediatric”进行检索，共识别出 542 项潜在研究。27 项回顾性研究符合纳入标准，包含年龄在 21 岁及以下的急性附睾炎或附睾炎患者。提取患者数量和年龄、尿液培养和尿液分析结果、接受抗生素治疗的患者数量和发病率。

结果

共确定了 1496 例急性附睾炎患者。对 1124 例患者进行了尿液分析，190 例（16.9%）为阳性。对 670 例患者进行了尿液培养，100 例（14.9%）为阳性。有 14 项研究涉及抗生素的使用，其中 652 例患有急性附睾炎，554 例（85%）接受了抗生素治疗。在 502 例有尿液分析结果、尿液培养结果和抗生素治疗率的患者中，有 54 例（10.8%）的细菌来源为阳性。对其中 502 例患者中的 410 例（81.7%）使用了抗生素。