比较不同人体测量学指标在识别学龄儿童血脂异常中的作用。
Comparison of different anthropometric indices for identifying dyslipidemia in school children.
机构信息
Nutrition and Diabetes Department, Hospital Durand, Buenos Aires, Argentina.
出版信息
Clin Biochem. 2011 Jun;44(8-9):659-64. doi: 10.1016/j.clinbiochem.2011.02.004. Epub 2011 Feb 22.
BACKGROUND
Anthropometric indices have been associated with dyslipidemia.
OBJECTIVE
To compare the abilities of BMI, waist circumference (WC) and WC/height to identify children's dyslipidemia.
METHODS
Students 1261 (639 male) age 9.5±2.1 years. were examined for anthropometry and lipid levels. Triglycerides ≥1.69 mmol/L and high-density lipoprotein cholesterol (HDL-C) <0.91 mmol/L were considered abnormal per American Heart Association.
RESULTS
The prevalence of abnormal triglycerides was 4.1% and HDL-C 8.1%. The areas under the receiver operator curves (ROC) were: BMI=0.87, WC=0.83, and WC/height=0.84 in predicting both low HDL-C and high triglycerides. Multiple regression analyses showed that the odds ratios (OR) were highest for WC [6.5], followed by WC/height [5.4], and BMI [4.9], for dyslipidemia.
CONCLUSIONS
The results suggest that WC, WC/height, and BMI similarly predicted dyslipidemia, using ROC analyses. However, regression analyses showed that WC followed by WC/height was most predictive of dyslipidemia.
背景
人体测量指数与血脂异常有关。
目的
比较 BMI、腰围（WC）和 WC/身高在识别儿童血脂异常方面的能力。
方法
对 1261 名（639 名男性）年龄为 9.5±2.1 岁的学生进行了人体测量和血脂水平检查。根据美国心脏协会的标准，甘油三酯≥1.69mmol/L 和高密度脂蛋白胆固醇（HDL-C）<0.91mmol/L 被认为异常。
结果
异常甘油三酯的患病率为 4.1%，HDL-C 为 8.1%。预测低 HDL-C 和高甘油三酯血症的受试者工作特征曲线（ROC）下面积分别为：BMI=0.87、WC=0.83 和 WC/身高=0.84。多元回归分析显示，WC 的比值比（OR）最高[6.5]，其次是 WC/身高[5.4]和 BMI[4.9]，提示血脂异常。
结论
ROC 分析表明，WC、WC/身高和 BMI 同样可以预测血脂异常，但回归分析显示 WC 和 WC/身高是血脂异常最具预测性的指标。
Zotero 插件