Ledoux M, Lambert J, Reeder B A, Després J P
Département de Nutrition, Faculté de Médecine, Université de Montréal, Que.
CMAJ. 1997 Jul 1;157 Suppl 1:S32-8.
To determine the mathematic formula for weight, height and waist and hip circumference that is most closely correlated to cardiovascular disease risk factors.
Population-based, cross-sectional surveys.
Five Canadian provinces, between 1990 and 1992.
A probability sample of 16,007 men and women aged 18 to 74 years was selected using health insurance registration files in each province. Anthropometry was performed on 10,054 (63%) of these adults.
The power of height in the body mass index (BMI, kg/m2) and of hip circumference in the ratio of waist to hip circumference (WC/HC) was varied from 0 to 3. Simple linear regression analysis for each age-sex group was used to examine the relation of each index to systolic and diastolic blood pressure (SBP and DBP), levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL) and high-density lipoprotein cholesterol (HDL), triglycerides (TRIG) and the ratio of TC to HDL. Values for the coefficient of determination (r2) were used to compare the fits of the models.
The r2 values were generally low (< 0.27), but were greatest in the younger age groups (18-24 and 35-54 years) and in women. Waist circumference alone (WC/HC0) showed the best fit with SBP and DBP, whereas WC/HC0.5 was most closely related to HDL, TC/HDL and TRIG. None of the indices was closely associated with TC or LDL. Whatever the power of height used, the weight-height ratios showed weaker associations with the risk factors than the waist-hip ratios.
WC and BMI correlate most closely with blood pressure and plasma lipid and may be the best simple anthropometric indices to include in the routine clinical examination of adults.
确定与心血管疾病风险因素最密切相关的体重、身高以及腰围和臀围的数学公式。
基于人群的横断面调查。
1990年至1992年期间加拿大的五个省份。
利用每个省份的健康保险登记档案,选取了16007名年龄在18至74岁之间的男性和女性作为概率样本。对其中10054名(63%)成年人进行了人体测量。
体重指数(BMI,kg/m²)中身高的幂次以及腰臀比(WC/HC)中臀围的幂次在0至3之间变化。对每个年龄性别组进行简单线性回归分析,以检验每个指标与收缩压和舒张压(SBP和DBP)、总胆固醇(TC)水平、低密度脂蛋白胆固醇(LDL)、高密度脂蛋白胆固醇(HDL)、甘油三酯(TRIG)以及TC与HDL的比值之间的关系。用决定系数(r²)值来比较模型的拟合优度。
r²值总体较低(<0.27),但在较年轻年龄组(18 - 24岁和35 - 54岁)以及女性中最高。单独的腰围(WC/HC0)与SBP和DBP的拟合度最佳,而WC/HC0.5与HDL、TC/HDL和TRIG的关系最为密切。没有一个指标与TC或LDL密切相关。无论身高的幂次如何使用,体重身高比与风险因素的关联都比腰臀比弱。
WC和BMI与血压及血脂的相关性最为密切,可能是成年人常规临床检查中最好的简单人体测量指标。