Park Soo Yuck, Eun Chang Soo, Byun Young Sang, Yoon Ji Young, Jeon Yong Cheol, Han Dong Soo, Sohn Joo Hyun, Oh Young Ha
Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.
Korean J Gastroenterol. 2011 Feb;57(2):115-9. doi: 10.4166/kjg.2011.57.2.115.
The simultaneous occurrence of primary gastric lymphoma and adenocarcinoma is rarely reported. We here report a case of synchronous double primary tumor of advanced gastric cancer and diffuse large B cell lymphoma. A 65-year-old woman underwent an esophagogastroduodenoscopy for the evaluation of abdominal discomfort of two months' duration. The endoscopic examination showed an ulcerating tumor in the gastric antrum and thickened folds in the fundus and the microscopic examination revealed an adenocarcinoma in the antrum and a diffuse large B-cell lymphoma in the fundus. She has had total gastrectomy and CHOP chemotherapy with rituximab. Since the cases of synchronous double primary gastric tumors have been increased on the recent medical advances, when a gastric tumor is detected for the endoscopic examination, an endoscopist has to make every endeavor not to miss another tumor in the stomach.
原发性胃淋巴瘤与腺癌同时发生的情况鲜有报道。我们在此报告一例晚期胃癌与弥漫性大B细胞淋巴瘤同步双原发肿瘤的病例。一名65岁女性因持续两个月的腹部不适接受了食管胃十二指肠镜检查。内镜检查显示胃窦有溃疡性肿瘤,胃底皱襞增厚,显微镜检查发现胃窦为腺癌,胃底为弥漫性大B细胞淋巴瘤。她接受了全胃切除术及含利妥昔单抗的CHOP化疗。鉴于近年来随着医学进步同步双原发胃肿瘤病例有所增加,在内镜检查发现胃肿瘤时,内镜医师必须尽一切努力不漏诊胃内的其他肿瘤。