Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal.
Phys Chem Chem Phys. 2011 Mar 28;13(12):5462-71. doi: 10.1039/c1cp20418a. Epub 2011 Feb 25.
The phenazine monomers neutral red (NR) and methylene blue (MB) have been electropolymerised on different quartz crystal microbalance (QCM) substrates: MB at AuQCM and nanostructured ultrathin sputtered carbon AuQCM (AuQCM/C), and NR on AuQCM and on layer-by-layer films of hyaluronic acid with myoglobin deposited on AuQCM (AuQCM-{HA/Mb}(6)). The surface of the electrode substrates was characterised by atomic force microscopy (AFM), and the frequency changes during potential cycling electropolymerisation of the monomer were monitored by the QCM. The study investigates how the monomer chemical structure together with the electrode morphology and surface structure can influence the electropolymerisation process and the electrochemical properties of the phenazine-modified electrodes. Differences between MB and NR polymerisation, as well as between the different substrates were found. The electrochemical properties of the PNR-modified electrodes were analysed by cyclic voltammetry and electrochemical impedance spectroscopy and compared with the unmodified AuQCM. The results are valuable for future applications of modified AuQCM as substrates for electroactive polymer film deposition and applications in redox-mediated electrochemical sensors and biosensors.
吩嗪单体中性红（NR）和亚甲蓝（MB）已在不同的石英晶体微天平（QCM）基底上进行电聚合：MB 在 AuQCM 和纳米结构超薄溅射碳 AuQCM（AuQCM/C）上，NR 在 AuQCM 和在金上沉积有肌红蛋白的透明质酸层层薄膜（AuQCM-{HA/Mb}(6))。通过原子力显微镜（AFM）对电极基底的表面进行了表征，并通过 QCM 监测了单体在电位循环电聚合过程中的频率变化。该研究调查了单体化学结构以及电极形态和表面结构如何影响吩嗪修饰电极的电聚合过程和电化学性质。发现 MB 和 NR 聚合之间以及不同基底之间存在差异。通过循环伏安法和电化学阻抗谱分析了 PNR 修饰电极的电化学性质，并与未修饰的 AuQCM 进行了比较。这些结果对于将修饰后的 AuQCM 作为电活性聚合物薄膜沉积的基底以及在氧化还原介导的电化学传感器和生物传感器中的应用具有重要价值。
