Farooq Uzma, Laureano Ana C, Miteva Mariya, Elgart George W
Kendall Medical Laboratory, Coral Gables, FL, USA.
J Cutan Pathol. 2011 Jun;38(6):525-8. doi: 10.1111/j.1600-0560.2011.01681.x. Epub 2011 Feb 24.
Endometriosis is a condition where endometrial glands and stroma are ectopically located in sites other than the uterine cavity. Cutaneous endometriosis is very rare, representing approximately 1.1% of cases of extrapelvic endometriosis. We report a case of a 44-year-old female with no prior surgical history who presented with multiple tan brown periumbilical nodules. Histopathological examination revealed multiple glandular structures in the dermis with surrounding stroma. Immunohistochemistry cinches the diagnosis, as CD10, estrogen receptor and progesterone receptor are strongly positive in our case. The mainstay of treatment of cutaneous endometriosis is surgical excision of the lesion.
子宫内膜异位症是指子宫内膜腺体和间质异位种植于子宫腔以外的部位。皮肤子宫内膜异位症非常罕见，约占盆腔外子宫内膜异位症病例的1.1%。我们报告一例44岁无手术史的女性，其脐周出现多个棕褐色结节。组织病理学检查显示真皮内有多个腺体结构及周围间质。免疫组化确诊了该病，因为在我们的病例中，CD10、雌激素受体和孕激素受体均呈强阳性。皮肤子宫内膜异位症的主要治疗方法是手术切除病灶。
