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宠物犬 6 分钟步行试验评估。

Evaluation of the 6-minute walk test in pet dogs.

机构信息

Section of Critical Care, Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA.

出版信息

J Vet Intern Med. 2011 Mar-Apr;25(2):405-6. doi: 10.1111/j.1939-1676.2011.0689.x. Epub 2011 Feb 25.

Abstract

BACKGROUND

The 6-minute walk test (6MWT) is widely used in human medicine to objectively assess the degree of impairment, and to provide objective evidence of disease progression or response to therapy.

HYPOTHESIS/OBJECTIVES: The 6MWT will be easy to perform and well-tolerated in pet dogs. Dogs with pulmonary disease will walk shorter distances than healthy dogs.

ANIMALS

Sixty-nine healthy dogs were recruited from the hospital community. Six dogs with mild to moderate pulmonary disease were recruited from animals presented for evaluation at the teaching hospital.

METHODS

Prospective study. Dogs walked for 6 minutes in a hallway and the distance covered was measured. Pulse oximetry and heart rate were recorded before and after walking. Physical characteristics of the dogs, including age, leg length, body condition score, and weight, were recorded. Healthy dogs were compared with affected dogs by a Student's t-test (P < .05). Correlations were calculated between the age, physical characteristics, and distances walked in the healthy dogs.

RESULTS

Healthy dogs walked 522.7 ± 52.4 m, while sick dogs (n = 6) walked 384.8 ± 41.0 m (P < .001). There was low (r = 0.13) to moderate (r= 0.27) correlation in the healthy dogs between physical characteristics and distances walked.

CONCLUSIONS AND CLINICAL IMPORTANCE

The 6MWT was easy to perform and discriminated between healthy dogs and dogs with pulmonary disease.

摘要

背景

6 分钟步行试验(6MWT)广泛应用于人类医学,以客观评估损伤程度,并提供疾病进展或治疗反应的客观证据。

假设/目的:6MWT 将易于在宠物犬中进行,且犬只易于耐受。患有肺部疾病的犬比健康犬行走的距离更短。

动物

从医院社区招募了 69 只健康犬。从教学医院就诊的动物中招募了 6 只患有轻度至中度肺部疾病的犬。

方法

前瞻性研究。犬在走廊中行走 6 分钟,测量其行走距离。行走前后记录脉搏血氧饱和度和心率。记录犬的身体特征,包括年龄、腿长、身体状况评分和体重。通过学生 t 检验(P <.05)比较健康犬和患病犬。计算健康犬的年龄、身体特征与行走距离之间的相关性。

结果

健康犬行走 522.7 ± 52.4 m,而患病犬(n = 6)行走 384.8 ± 41.0 m(P <.001)。健康犬的身体特征与行走距离之间存在低(r = 0.13)到中度(r= 0.27)的相关性。

结论和临床意义

6MWT 易于进行,可区分健康犬和患有肺部疾病的犬。

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