Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
J Vet Intern Med. 2011 Mar-Apr;25(2):187-98. doi: 10.1111/j.1939-1676.2011.0695.x. Epub 2011 Feb 25.
Anecdotal beliefs and limited research suggest variable patterns of mortality in age, size, and breed cohorts of dogs. Detailed knowledge of mortality patterns would facilitate development of tailored health-maintenance practices and contribute to the understanding of the genetic basis of disease.
HYPOTHESIS/OBJECTIVES: To describe breed-specific causes of death in all instances of canine mortality recorded in the Veterinary Medical Database (VMDB)(a) between 1984 and 2004. We hypothesized that causes of death, categorized by organ system (OS) or pathophysiologic process (PP), would segregate by age, body mass, and breed.
74,556 dogs from the VMDB for which death was the outcome of the recorded hospital visit.
Retrospective study. Causes of death from abstracted VMDB medical records were categorized by OS and PP and analyzed by age, breed, and breed-standard mass of dog.
Causes of death, categorized by OS or PP, segregated by age, breed, and breed-standard mass. Young dogs died more commonly of gastrointestinal and infectious causes whereas older dogs died of neurologic and neoplastic causes. Increasing age was associated with an increasing risk of death because of cardiovascular, endocrine, and urogenital causes, but not because of hematopoietic or musculoskeletal causes. Dogs of larger breeds died more commonly of musculoskeletal and gastrointestinal causes whereas dogs of smaller breeds died more commonly of endocrine causes.
Not all causes of death contribute equally to mortality within age, size, or breed cohorts. Documented patterns now provide multiple targets for clinical research and intervention.
一些传闻和有限的研究表明，狗在年龄、体型和品种群体中的死亡率存在不同的模式。详细了解死亡率模式将有助于制定针对性的健康维护措施，并有助于了解疾病的遗传基础。
假设/目的：描述在兽医医疗数据库（VMDB）记录的所有犬只死亡病例中，特定品种的死亡原因（a）在 1984 年至 2004 年之间。我们假设，按器官系统（OS）或病理生理过程（PP）分类的死因将按年龄、体重和品种进行分类。
VMDB 中 74556 只因记录的医院就诊而死亡的狗。
回顾性研究。从 VMDB 摘录的病历中死亡原因按 OS 和 PP 进行分类，并按年龄、品种和犬标准体重进行分析。
按 OS 或 PP 分类的死因按年龄、品种和品种标准体重进行分类。幼犬更常见于死于胃肠道和传染病，而老年犬则死于神经和肿瘤疾病。随着年龄的增长，死于心血管、内分泌和泌尿生殖系统疾病的风险增加，但死于血液和骨骼肌肉系统疾病的风险没有增加。体型较大的犬死于肌肉骨骼和胃肠道疾病的可能性更大，而体型较小的犬死于内分泌疾病的可能性更大。
并非所有死因都同等地导致年龄、体型或品种群体中的死亡率。记录的模式现在为临床研究和干预提供了多个目标。
