Liebermann B, Röthig W, Kaufhold W
Bereichs Medizin (Charitè) der Humboldt-Universität zu Berlin.
Dtsch Z Mund Kiefer Gesichtschir. 1990 Nov-Dec;14(6):418-23.
The value of ultra short antimicrobial prophylaxis using azlocillin in preventing postoperative wound infections was studied in a prospective clinical/bacteriological study in 41 orthognathic operations. Preoperatively the oral mucosa and pharyngeal flora of each patient was subjected to bacteriological identification with particular emphasis on anaerobes and sensitivity tests for organisms with established pathogenic potential. The results of a bacteriological examination of the redon drains on day 1 postoperatively indicated a contamination of the surgical wound. Clinically 31 patients showed moderate postoperative edema of the buccal soft tissues and 10 patients had hematomas or hemorrhages. In all patients the operation was followed by primary intraoral wound healing without any signs of an early infection.
在一项针对41例正颌手术的前瞻性临床/细菌学研究中，对使用阿洛西林进行超短抗菌预防以防止术后伤口感染的价值进行了研究。术前对每位患者的口腔黏膜和咽部菌群进行细菌学鉴定，特别着重于厌氧菌以及对具有确定致病潜力的微生物进行敏感性测试。术后第1天对引流管进行的细菌学检查结果表明手术伤口受到污染。临床上，31例患者出现颊部软组织中度术后水肿，10例患者有血肿或出血。所有患者术后口腔内伤口均一期愈合，无任何早期感染迹象。
