Department of Health Sciences VU University, Amsterdam, the Netherlands.
Health Qual Life Outcomes. 2011 Feb 27;9:11. doi: 10.1186/1477-7525-9-11.
During the past decade, quality of life (QoL) has become an accepted measure of disease impact, therapeutic outcome, and evaluation of interventions. So far, very little is known about the effects of community-based interventions on people's QoL. Therefore, the effect of an integrative cardiovascular diseases community-based intervention programme 'Hartslag Limburg' on QoL after 5-years of intervention is studied.
A longitudinal cohort study comparing 5-year mean change in QoL between the intervention (n = 2356) and reference group (n = 758). QoL outcomes were the physical and mental health composite scores (PCS and MCS) measured by the RAND-36. Analyses were stratified for gender and socio-economic status (SES).
After 5-years of intervention we found no difference in mean change in PCS and MCS between the intervention and reference group in both genders and low-SES. However, for the moderate/high SES intervention group, the scales social functioning (-3.6, 95% CI:-6.1 to -1.2), physical role limitations (-5.3, 95% CI:-9.6 to -1.0), general mental health (-3.0, 95% CI:-4.7 to -1.3), vitality (-3.2, 95% CI:-5.1 to -1.3), and MCS (-1.8, 95% CI:-2.9 to -0.6) significantly changed compared with the reference group. These differences were due to a slight decrease of QoL in the intervention group and an increase of QoL in the reference group.
Hartslag Limburg has no beneficial effect on people's physical and mental QoL after 5-years of intervention. In fact, subjects in the intervention group with a moderate/high SES, show a decrease on their mental QoL compared with the reference group.
在过去的十年中，生活质量（QoL）已成为衡量疾病影响、治疗效果和干预措施评估的公认指标。到目前为止，人们对基于社区的干预措施对人们生活质量的影响知之甚少。因此，研究了基于社区的综合心血管疾病干预计划“Hartslag Limburg”对干预 5 年后生活质量的影响。
一项纵向队列研究比较了干预组（n=2356）和对照组（n=758）5 年生活质量平均变化。生活质量结果是通过 RAND-36 测量的身体和心理健康综合评分（PCS 和 MCS）。分析按性别和社会经济地位（SES）分层。
干预 5 年后，我们发现男女和低 SES 组干预组和对照组在 PCS 和 MCS 的平均变化方面没有差异。然而，对于中/高 SES 干预组，量表社会功能（-3.6，95%CI：-6.1 至-1.2）、身体角色限制（-5.3，95%CI：-9.6 至-1.0）、一般心理健康（-3.0，95%CI：-4.7 至-1.3）、活力（-3.2，95%CI：-5.1 至-1.3）和 MCS（-1.8，95%CI：-2.9 至-0.6）显著变化与对照组相比。这些差异是由于干预组的生活质量略有下降，对照组的生活质量有所提高。
Hartslag Limburg 在干预 5 年后对人们的身心健康生活质量没有有益的影响。事实上，SES 中/高的干预组的受试者的心理健康质量与对照组相比有所下降。
