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妊娠后腰痛症状的持续存在和定量超声测量的骨密度变化 - 一项为期两年的纵向随访研究。

Persistence of back pain symptoms after pregnancy and bone mineral density changes as measured by quantitative ultrasound--a two year longitudinal follow up study.

机构信息

Department of Obstetrics & Gynaecology, United Christian Hospital, Hip Wo Street, Kwun Tong, Hong Kong, PR China.

出版信息

BMC Musculoskelet Disord. 2011 Feb 28;12:55. doi: 10.1186/1471-2474-12-55.

DOI:10.1186/1471-2474-12-55
PMID:21352600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3053307/
Abstract

BACKGROUND

Previous research has shown a loss of bone mineral density (BMD) during pregnancy. This loss has been correlated to the occurrence of back pain symptoms during pregnancy. The objective of this study was to evaluate whether persistence of back pain symptoms 2 years after pregnancy could be associated with BMD changes as measured by quantitative USG of the os calcis.

METHODS

A cohort of patients who reported significant back pain symptoms during pregnancy were surveyed for persistent back pain symptoms 24 to 28 months after the index pregnancy. Os calcis BMD was measured by quantitative ultrasound and compared with the BMD values during pregnancy.

RESULTS

A cohort of 60 women who had reported significant back pain symptoms in their index pregnancy completed a 24-28 months follow-up survey and BMD reassessment. Persistence of significant back pain symptoms was seen in 24 (40%) of this cohort. These women had higher BMD loss during pregnancy compared to those without further pain (0.047 Vs 0.030 g/cm2; p = 0.03). Those that remained pain free after pregnancy appeared to have completely recovered their BMD loss in pregnancy, while those with persistent pain had lower BMD values (ΔBMD - 0.007 Vs - 0.025 g/cm2; p = 0.023) compared to their early pregnancy values.

CONCLUSION

Persistence of back pain symptoms after pregnancy could be related to an inability to recover fully from BMD loss during the index pregnancy.

摘要

背景

之前的研究表明,女性在怀孕期间会出现骨密度(BMD)下降。这种下降与怀孕期间出现背痛症状有关。本研究的目的是评估产后 24-28 个月背痛症状是否持续与跟骨定量超声(QUSG)测量的 BMD 变化有关。

方法

对报告在怀孕期间有明显背痛症状的患者队列进行调查,以了解其在指数妊娠后 24-28 个月时背痛症状是否持续存在。通过定量超声测量跟骨 BMD,并与怀孕期间的 BMD 值进行比较。

结果

报告在指数妊娠期间有明显背痛症状的 60 名女性完成了 24-28 个月的随访调查和 BMD 重新评估。该队列中有 24 名(40%)女性背痛症状持续存在。与无进一步疼痛的女性相比,这些女性在怀孕期间的 BMD 丢失更多(0.047 对 0.030 g/cm2;p = 0.03)。那些在怀孕后无疼痛的女性似乎已经完全恢复了怀孕期间的 BMD 丢失,而那些持续疼痛的女性的 BMD 值较低(ΔBMD -0.007 对 -0.025 g/cm2;p = 0.023),与早期妊娠值相比。

结论

产后背痛症状持续存在可能与无法从指数妊娠期间的 BMD 丢失中完全恢复有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e695/3053307/4c81453a1db4/1471-2474-12-55-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e695/3053307/4c81453a1db4/1471-2474-12-55-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e695/3053307/4c81453a1db4/1471-2474-12-55-1.jpg

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