Jianan Mental Hospital, Department of Health, Tainan, Taiwan.
Compr Psychiatry. 2011 Nov-Dec;52(6):662-9. doi: 10.1016/j.comppsych.2011.01.002. Epub 2011 Feb 24.
We used the population-based National Health Insurance database to investigate the prevalence, correlates, and disease patterns of antidepressant use in Taiwan.
The National Health Research Institutes provided a database of 200,000 random subjects for study. We obtained a random sample of 145,304 subjects 18 years or older in 2004. Study subjects who had been given at least 1 antidepressant drug prescription during this year were identified. We detected factors associated with any antidepressant use. We also examined the proportion of antidepressant use for psychiatric and medical disorders.
The 1-year prevalence of antidepressant use was 4.3%. Higher antidepressant use was found in the aged group, in female subjects, in individuals with a fixed premium and with an insurance amount lower than US $640, in individuals with disability, and among subjects in the central area. Among subjects with antidepressant use, the higher proportions of psychiatric disorders were for neurotic depression (21.1%), anxiety state (17.6%), major depressive disorder (14.6%), special symptoms or syndromes not elsewhere classified (8.5%), and depressive disorder not elsewhere classified (5.4%). With respect to medical disorders, the higher proportions of antidepressant use were for diseases of the genitourinary system; musculoskeletal system and connective tissue; symptoms, signs, and ill-defined conditions; circulatory system; endocrine, nutritional, and metabolic diseases and immunity disorders; and nervous system and sense organs.
Higher proportion of psychiatric disorders among subjects with antidepressant use were for depressive disorder and anxiety disorder. However, 39% of the subjects were using antidepressants for nonpsychiatric disorders in Taiwan.
我们利用基于人群的全民健康保险数据库，调查了在台湾使用抗抑郁药的流行率、相关性和疾病模式。
国家健康研究所提供了一个由 20 万名随机受试者组成的数据库。我们从 2004 年的数据库中随机抽取了 145304 名 18 岁及以上的受试者。确定了当年至少有 1 次抗抑郁药处方的研究对象。我们检测了与任何抗抑郁药使用相关的因素。我们还检查了抗抑郁药用于治疗精神和医学疾病的比例。
抗抑郁药的 1 年使用率为 4.3%。在年龄较大的人群、女性、固定保费和保险金额低于 640 美元的人群、残疾人和中心地区的人群中，抗抑郁药的使用比例较高。在使用抗抑郁药的患者中，精神障碍的比例较高的是神经症性抑郁症（21.1%）、焦虑状态（17.6%）、重性抑郁症（14.6%）、特殊症状或综合征不能归类于其他类别（8.5%）和不能归类于其他类别的抑郁症（5.4%）。对于医学疾病，抗抑郁药使用率较高的是泌尿生殖系统疾病；肌肉骨骼系统和结缔组织疾病；症状、体征和无法明确的情况；循环系统疾病；内分泌、营养和代谢疾病以及免疫障碍；以及神经系统和感觉器官疾病。
在使用抗抑郁药的患者中，精神障碍的比例较高的是抑郁障碍和焦虑障碍。然而，在台湾，39%的患者使用抗抑郁药治疗非精神疾病。
