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上皮性卵巢癌的化疗。

Chemotherapy in epithelial ovarian cancer.

机构信息

Division of Medical Oncology, Department of Urology and Gynecology, National Cancer Institute of Naples, Via Mariano Semmola, 80131 Naples, Italy.

出版信息

Cancer Lett. 2011 Apr 28;303(2):73-83. doi: 10.1016/j.canlet.2011.01.026. Epub 2011 Feb 24.

Abstract

Epithelial ovarian cancer is the most common type of ovarian cancer; usually occurs in women older than 50years, and because 75% of cases are diagnosed at stage III or IV it is associated with a poor prognosis. Treatment of ovarian cancer is based on the integration of surgery and chemotherapy. Chemotherapy plays a major role both in the adjuvant treatment and in the care of patients with advanced disease. Several active drugs have been introduced in the treatment of ovarian cancer in the last decades and novel targets and agents are under evaluation.

摘要

上皮性卵巢癌是最常见的卵巢癌类型;通常发生在 50 岁以上的女性中,由于 75%的病例在 III 期或 IV 期诊断,因此预后不良。卵巢癌的治疗基于手术和化疗的结合。化疗在辅助治疗和晚期疾病患者的治疗中都起着重要作用。在过去几十年中,已经引入了几种治疗卵巢癌的有效药物,并且正在评估新的靶点和药物。

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