Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Arch Phys Med Rehabil. 2011 Mar;92(3):509-15. doi: 10.1016/j.apmr.2010.07.243.
The authors look forward and discuss future directions in spinal cord injury (SCI) from a perspective of biomedical, psychosocial and technologic research. This discussion is based both on recent developments from various fields of knowledge and, more specifically, on SCI Model Systems' research contributions to medical rehabilitation. Biomedical research, as described here, includes (1) the process of moving from the "bench to bedside" and harnessing knowledge from basic science to produce new clinical treatment options for SCI during the life span; (2) the rapid proliferation of clinical trials aimed at neurologic recovery; (3) the growth of new technologies to restore and improve function; and (4) the challenges of developing relevant outcome measures to evaluate efficacy and effectiveness of interventions. Recent progress in psychosocial research has contributed significantly to understanding of the many factors associated with disability during the life course, the importance of quality of life issues, and the value of activity, participation, and the environment in promoting successful rehabilitation outcomes following SCI. Technology and bioengineering advances are discussed in relation to access to high-quality technology; restoration and replacement of movement; and technology to enhance rehabilitation outcomes.
作者从生物医学、心理社会和技术研究的角度展望和讨论脊髓损伤 (SCI) 的未来方向。这一讨论既基于各个知识领域的最新进展，也更具体地基于 SCI 模型系统对医学康复的研究贡献。这里描述的生物医学研究包括：(1) 将知识从基础科学应用于临床治疗的过程，以便在整个生命周期内为 SCI 提供新的临床治疗选择；(2) 旨在实现神经恢复的临床试验的迅速增多；(3) 恢复和改善功能的新技术的发展；以及 (4) 开发相关结果测量的挑战，以评估干预措施的效果和有效性。心理社会研究的最新进展极大地促进了对与残疾相关的许多因素的理解，包括生活过程中的残疾、生活质量问题的重要性以及活动、参与和环境在促进 SCI 后的成功康复结果方面的价值。还讨论了技术和生物工程方面的进展，涉及到高质量技术的获取、运动的恢复和替代以及增强康复效果的技术。
