Department of Cardiology, Gaziosmanpasa University School of Medicine, Tokat, Turkey.
Kaohsiung J Med Sci. 2011 Feb;27(2):55-8. doi: 10.1016/j.kjms.2010.12.003. Epub 2011 Feb 12.
We investigated the relationship between renal function and coronary thrombolysis in myocardial infarction frame count (TFC) in patients with slow coronary flow (SCF). The patient group was composed of 34 patients with SCF. The control group was made up of 34 well-matched individuals who have normal SCF in their coronary arteries. The coronary flow rates of all subjects were documented by TFC. Glomerular filtration rate (GFR) and corrected GFR (cGFR) were calculated by creatinine clearance according to the Cockcroft-Gault formula. There is no difference in the gender or age of the groups. Blood urea nitrogen and creatinine were significantly higher in the SCF group compared the control group (blood urea nitrogen: 17 ± 6 mg/dL vs. 14 ± 4 mg/dL, p=0.04 and creatine: 0.9 ± 0.1mg/dL vs. 0.7 ± 0.1mg/dL, p=0.01). GFR and cGFR were significantly different between the groups (GFR: 92 ± 28 mL/min vs. 112 ± 27 mL/min, p=0.004 and cGFR: 77 ± 22 mL/min/1.73 m(2)vs. 96 ± 24 mL/min/1.73 m(2), p=0.007). There was a negative correlation between GFR/cGFR and TFC in all coronary arteries. This study shows that impaired renal function is associated with SCF. Patients with SCF have worse renal function compared with patients without SCF.
我们研究了肾功能与冠状动脉慢血流（SCF）患者中的心肌梗死帧数（TFC）之间的关系。患者组由 34 例 SCF 患者组成。对照组由 34 例冠状动脉正常的匹配个体组成。所有受试者的冠状动脉血流率均通过 TFC 记录。肾小球滤过率（GFR）和校正的 GFR（cGFR）根据 Cockcroft-Gault 公式通过肌酐清除率计算。两组的性别或年龄无差异。与对照组相比，SCF 组的血尿素氮和肌酐显着升高（血尿素氮：17±6mg/dL 与 14±4mg/dL，p=0.04 和肌酐：0.9±0.1mg/dL 与 0.7±0.1mg/dL，p=0.01）。两组之间的 GFR 和 cGFR 显着不同（GFR：92±28mL/min 与 112±27mL/min，p=0.004 和 cGFR：77±22mL/min/1.73m(2)与 96±24mL/min/1.73m(2)，p=0.007）。所有冠状动脉的 GFR/cGFR 与 TFC 呈负相关。这项研究表明，肾功能受损与 SCF 有关。与无 SCF 患者相比，SCF 患者的肾功能更差。
