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脑氧饱和度监测联合清醒试验在局部麻醉下颈动脉内膜切除术患者中的作用。

The role of cerebral oximetry in combination with awake testing in patients undergoing carotid endarterectomy under local anaesthesia.

机构信息

Department of Vascular Surgery, King's College Hospital, Denmark Hill, London SE5 9RS, UK.

出版信息

Eur J Vasc Endovasc Surg. 2011 May;41(5):599-605. doi: 10.1016/j.ejvs.2010.12.009. Epub 2011 Feb 26.

Abstract

INTRODUCTION

The aim of this study is to analyse the role of cerebral oximetry in combination with awake testing in detecting cerebral ischaemia in patients undergoing carotid endarterectomy (CEA) under local anaesthesia (LA).

METHODS

One hundred consecutive patients scheduled for CEA under LA were investigated. Regional oxygen saturation (rSO(2)) was measured with a cerebral oximeter. Cerebral ischaemia was assessed by awake testing in conjunction with rSO(2). Shunting was based solely on deterioration in conscious state assessed by awake testing. The correlation between awake testing and percentage fall in rSO(2) levels was statistically analysed.

RESULTS

Patients requiring general anaesthesia were excluded from analysis (n = 17). Seven patients developed deterioration in conscious state and an immediate drop in rSO(2) ≥20% following carotid cross-clamping. Two patients requiring shunting for non-neurological reasons were excluded from analysis. Two patients had a drop in rSO(2) ≥20%, but remained conscious and were not shunted. There were no permanent neurological deficits postoperatively. Statistical analysis showed a sensitivity of 100% with a specificity of 96% yielding a positive predictive value of 81% and negative predictive value of 100% for a ≥19% drop in rSO(2).

CONCLUSION

Cerebral oximetry using a cut off ≥19% drop in rSO(2) has a high sensitivity and specificity when compared with awake testing.

摘要

介绍

本研究旨在分析在局部麻醉(LA)下进行颈动脉内膜切除术(CEA)时,脑氧饱和度监测与清醒测试联合应用对检测脑缺血的作用。

方法

对 100 例行 LA-CEA 的连续患者进行研究。使用脑氧饱和度计测量局部氧饱和度(rSO₂)。通过与 rSO₂ 相结合的清醒测试评估脑缺血。根据清醒测试评估的意识状态恶化情况进行分流,而不考虑 rSO₂ 水平的百分比下降。统计分析清醒测试与 rSO₂ 水平下降百分比之间的相关性。

结果

排除需要全身麻醉的患者(n=17)。7 例患者在颈动脉夹闭后出现意识状态恶化和 rSO₂立即下降≥20%。因非神经原因需要分流的 2 例患者被排除在分析之外。2 例患者 rSO₂ 下降≥20%,但仍保持清醒且未进行分流。术后无永久性神经功能缺损。统计分析显示,rSO₂ 下降≥19%的敏感度为 100%,特异性为 96%,阳性预测值为 81%,阴性预测值为 100%。

结论

与清醒测试相比,rSO₂ 下降≥19%的脑氧饱和度监测具有较高的敏感度和特异性。

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