Department of Neurology, Pendeli Children's Hospital, 8 Mandelara Street, Nea Erythraia, 14671 Athens, Greece.
Eur J Paediatr Neurol. 2011 Jul;15(4):338-44. doi: 10.1016/j.ejpn.2011.02.004. Epub 2011 Feb 26.
There is great demand for effective management of children with Autistic Spectrum Disorders (ASD). This study aimed to investigate the effect of an individually tailored psycho-educational program for autistic children on the scores of the Childhood Autism Rating Scale (CARS) and the Short Sensory Profile (SSP).
Forty children (36 males) were enrolled into an intervention program which consisted of occupational therapy including sensory integration techniques, speech therapy, social skills therapy and parent-directed approaches. Autism severity was assessed using CARS; sensory response capability with the SSP pre- and post-treatment.
Eight children were intellectually normal; 12 borderline and 20 of low intelligence. Pre-treatment CARS showed that 8 were mildly autistic, 32 moderately-severely autistic. Post-treatment, 24 children changed category; 11 were no longer autistic. The percentage of children performing in the definitive difference region, according to total SSP score, changed slightly (45% vs 32.5%). Comparison of the pre- and post-treatment values revealed that CARS decreased significantly (p < 0.001), whereas total SSP did not (p = 0.294). Tactile sensitivity and low energy/weakness sections, though, were significantly different pre- and post-treatment. Longitudinal analysis, taking into account other confounding factors besides time, further revealed a significant decrement for CARS score with time but not for SSP score (p < 0.001 and p = 0.288, respectively). Similarly, intelligence levels affected CARS but not SSP values (p < 0.001 and p = 0.813, respectively).
Individually tailored psycho-educational therapy had a significant effect on autism severity according to CARS. Changes in the SSP scores were not significant.
对于患有自闭症谱系障碍（ASD）的儿童，有效的管理需求巨大。本研究旨在探讨针对自闭症儿童的个性化心理教育计划对儿童自闭症评定量表（CARS）和短感觉剖面（SSP）评分的影响。
共有 40 名儿童（36 名男性）参加了干预计划，该计划包括职业治疗，包括感觉统合技术、言语治疗、社交技能治疗和家长指导方法。自闭症严重程度使用 CARS 进行评估；治疗前后使用 SSP 评估感觉反应能力。
8 名儿童智力正常；12 名边缘智力和 20 名低智力。治疗前 CARS 显示，8 名儿童轻度自闭症，32 名儿童中度至重度自闭症。治疗后，24 名儿童改变类别；11 名儿童不再患有自闭症。根据总 SSP 评分，处于明确差异区域的儿童比例略有变化（45%比 32.5%）。治疗前后值的比较表明，CARS 显著降低（p < 0.001），而总 SSP 没有（p = 0.294）。然而，触觉敏感性和低能量/虚弱部分在治疗前后有显著差异。考虑到时间以外的其他混杂因素的纵向分析进一步表明，CARS 评分随时间显著下降，但 SSP 评分没有（分别为 p < 0.001 和 p = 0.288）。同样，智力水平影响 CARS 但不影响 SSP 值（分别为 p < 0.001 和 p = 0.813）。
根据 CARS，个性化心理教育治疗对自闭症严重程度有显著影响。SSP 评分的变化不显著。
