Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232-0615, USA.
Cell Metab. 2011 Mar 2;13(3):235-6. doi: 10.1016/j.cmet.2011.02.007.
The hypothalamic arcuate nucleus is a complex structure containing both orexigenic and anorexigenic neurons, coordinately regulated by leptin and energy state. In their recent Nature Neuroscience study, Aponte et al. (2011) use optogenetic technology to provide a glimpse into the consequences of exclusive activation of either NPY/AgRP or POMC neurons.
下丘脑弓状核是一个包含食欲刺激和食欲抑制神经元的复杂结构，由瘦素和能量状态协调调节。在他们最近的《自然神经科学》研究中，Aponte 等人（2011）使用光遗传学技术观察到单独激活 NPY/AgRP 或 POMC 神经元的后果。
