Deb Prabal, Sahni Hirdesh, Bhatoe Harjinder Singh
Department of Pathology, Armed Forces Medical College, Pune, India.
J Cancer Res Ther. 2010 Oct-Dec;6(4):560-3. doi: 10.4103/0973-1482.77074.
We hereby report an extremely unusual case of cystic angiomatous meningioma in the CPA region in a 58-year-old male patient. He presented with complaints of headache, repeated episodes of vomiting and increasing unsteadiness of gait. Neuroimaging showed a large multicystic left-sided tentorial tumor projecting into the cerebellum and CPA with contrast-enhancing peripheral solid rim. He underwent a left retromastoid craniectomy and total excision of the tumor. Histopathology revealed an angiomatous meningioma with predominant microvascular component and extensive cystic changes. Immunopositivity for epithelial membrane antigen (EMA), vimentin and S-100 protein proved vital in excluding a hemangioblastoma.
我们在此报告一例极为罕见的58岁男性患者,其CPA区发生囊性血管母细胞瘤。他主诉头痛、反复呕吐发作以及步态不稳加重。神经影像学检查显示左侧小脑幕有一个巨大的多囊性肿瘤,突入小脑和CPA区,周边实性边缘有强化。他接受了左乳突后颅骨切除术及肿瘤全切术。组织病理学显示为血管母细胞瘤,以微血管成分为主,并有广泛的囊性改变。上皮膜抗原(EMA)、波形蛋白和S-100蛋白的免疫阳性对于排除血管母细胞瘤至关重要。