Department of Otology, Neurotology and Skull Base Surgery, Queen Elizabeth Hospital, University Hospital Birmingham, United Kingdom.
Otol Neurotol. 2011 Jun;32(4):670-5. doi: 10.1097/MAO.0b013e31821179e0.
To assess the long-term outcome of lipomas affecting the cerebellopontine angle (CPA) and internal auditory canal (IAC).
This is a retrospective, single-center study of 10 CPA and IAC lipomas that have presented for the last 6 years. There were 8 male and 2 female patients whose age ranged from 22 to 71 years. These lesions were distributed equally between left and right sides.
The natural progression, audiovestibular signs and symptoms, imaging characteristics, and management options have been evaluated.
Long-term clinical outcome was correlated with serial imaging and audiograms.
The most common presenting feature was hearing loss with an average lesion size of 8 mm. Two patients experienced imbalance, with one requiring operative intervention for incapacitating vertigo. The other 9 were managed conservatively. Follow-up imaging was available for 8 cases, and no growth was observed in any of these, with an average follow-up of 3.5 years.
Because of the resolution of modern imaging, lipomas of the IAC and CPA are increasingly being recognized and accurately diagnosed. Our data suggest that these lesions are more common than previously thought, representing approximately 1% of all lesions in this location referred to our center. With the absence of growth in 8 cases with follow-up average of 3.5 years as our basis, we recommend that these lesions are managed conservatively by serial imaging. In rare cases, surgery may be required if the lesion is resulting in incapacitating symptoms, such as significant balance disturbance.
评估影响桥小脑角（CPA）和内听道（IAC）的脂肪瘤的长期预后。
这是一项回顾性、单中心研究，共纳入了过去 6 年来就诊的 10 例 CPA 和 IAC 脂肪瘤患者。其中 8 例为男性，2 例为女性，年龄 22 至 71 岁。这些病变在左侧和右侧的分布均匀。
评估了病变的自然进展、听觉和前庭症状、影像学特征和治疗选择。
长期临床结果与连续影像学和听力图相关联。
最常见的首发症状是听力损失，平均病变大小为 8mm。2 例患者出现平衡障碍，其中 1 例因无法控制的眩晕需要手术干预，其他 9 例则接受了保守治疗。8 例患者可获得随访影像学资料，在这些患者中均未观察到病变生长，平均随访时间为 3.5 年。
由于现代影像学的分辨率提高，IAC 和 CPA 的脂肪瘤越来越多地被识别和准确诊断。我们的数据表明，这些病变比以前认为的更为常见，在我们中心，它们约占该部位所有病变的 1%。根据 8 例具有 3.5 年平均随访时间的无生长病例，我们建议对这些病变进行连续影像学检查的保守治疗。在罕见情况下，如果病变导致严重的平衡障碍等致残症状，可能需要手术治疗。
