Department of Internal Medicine, Chungbuk National University School of Medicine, Cheongju, Korea.
Korean Circ J. 2011 Jan;41(1):38-42. doi: 10.4070/kcj.2011.41.1.38. Epub 2011 Jan 31.
Sparganosis is caused by a larval tapeworm of the genus Spirometra, which commonly invades subcutaneous tissue, but less frequently invades muscle, intestines, spinal cord, and the peritoneopleural cavity. The authors managed a female patient who presented with a recurrent pericardiopleural effusion and peripheral eosinophilia. The anti-sparganum-specific IgG serum level was significantly higher than normal control levels. In this patient, sparganosis was caused by the ingestion of raw frogs in an effort to control her thyroid disease. The recurrent pericardiopleural effusion and peripheral eosinophilia were controlled by 3 consecutive doses of praziquantel (75 mg/kg/day). The patient is doing well 4 years after presentation. Sparganosis should be considered a rare, but possible cause of recurrent pericardial effusion and peripheral eosinophilia. Immunoserologic testing using enzyme linked immunosorbent assays can be helpful in diagnosing human sparganosis, especially in cases without a subcutaneous lump or mass. Praziquantel is an alternative treatment for sparganosis in surgically-unresectable cases.
裂头蚴病是由裂头绦虫属的幼虫引起的，裂头绦虫属的幼虫通常侵犯皮下组织，但较少侵犯肌肉、肠道、脊髓和腹膜腔。作者治疗了一名女性患者，该患者表现为复发性心包积脓和外周血嗜酸性粒细胞增多。抗裂头蚴特异性 IgG 血清水平明显高于正常对照水平。在该患者中，裂头蚴病是由于摄入生青蛙以控制甲状腺疾病引起的。连续 3 剂吡喹酮（75mg/kg/天）治疗后，复发性心包积脓和外周血嗜酸性粒细胞增多得到控制。患者在就诊后 4 年情况良好。裂头蚴病应被视为复发性心包积液和外周血嗜酸性粒细胞增多的罕见但可能的原因。酶联免疫吸附试验等免疫血清学检测有助于诊断人体裂头蚴病，尤其是在无皮下肿块或肿块的情况下。对于无法手术切除的裂头蚴病病例，吡喹酮是一种替代治疗方法。
