RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
Chem Commun (Camb). 2011 Apr 7;47(13):3828-30. doi: 10.1039/c1cc10245a. Epub 2011 Feb 28.
The design of biologically inspired, multi-component cascade reactions enables the targeted synthesis of assorted structurally complex products. Similar to regulation in cells the reaction path is controlled by the substrate concentration and complex enantiopure products with high structural diversity are provided.
受生物启发的多组分级联反应的设计能够实现各种结构复杂的目标产物的定向合成。类似细胞中的调控,反应途径受底物浓度的控制,并提供具有高结构多样性的复杂对映纯产物。