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胃肠胰神经内分泌肿瘤:多模态影像学特征与病理相关性。

Gastroenteropancreatic neuroendocrine tumors: multimodality imaging features with pathological correlation.

机构信息

Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA.

出版信息

Jpn J Radiol. 2011 Feb;29(2):85-91. doi: 10.1007/s11604-010-0522-1. Epub 2011 Feb 27.

DOI:10.1007/s11604-010-0522-1
PMID:21359932
Abstract

Neuroendocrine tumors of the gastrointestinal tract are rare entities. Functioning neuroendocrine tumors tend to present early because of hormone-induced clinical symptoms, but detection of the primary lesion may be difficult owing to their small size. Neuroendocrine tumors are typically hypervascular and show enhancement after contrast administration on computed tomography (CT) or magnetic resonance imaging (MRI). Large nonfunctioning tumors may be found in asymptomatic patients. In such cases, the synchronous presence of hypervascular hepatic metastases should be explored. This pictorial review illustrates imaging features of functioning and nonfunctioning neuroendocrine tumors arising in the gastrointestinal tract and the pancreas. Modalities included are CT, MRI, ultrasonography, and nuclear medicine. Characteristic histological specimens of these lesions are presented.

摘要

胃肠道神经内分泌肿瘤较为罕见。功能性神经内分泌肿瘤由于激素诱导的临床症状而往往较早出现,但由于其体积较小,原发灶的检测可能较为困难。神经内分泌肿瘤通常为富血管性肿瘤,在 CT 或 MRI 增强扫描后可见强化。无症状患者可能会发现大的无功能性肿瘤。在这种情况下,应探索是否存在富血管性肝转移。本影像学综述阐述了胃肠道和胰腺来源的功能性和无功能性神经内分泌肿瘤的影像学特征。包括 CT、MRI、超声和核医学。还呈现了这些病变的典型组织学标本。

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本文引用的文献

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Functional imaging of neuroendocrine tumors: a head-to-head comparison of somatostatin receptor scintigraphy, 123I-MIBG scintigraphy, and 18F-FDG PET.神经内分泌肿瘤的功能成像:生长抑素受体闪烁显像、123I-MIBG 闪烁显像和 18F-FDG PET 的头对头比较。
J Nucl Med. 2010 May;51(5):704-12. doi: 10.2967/jnumed.109.069765. Epub 2010 Apr 15.
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Imaging of NETs with PET radiopharmaceuticals.使用PET放射性药物对神经内分泌肿瘤进行成像。
Q J Nucl Med Mol Imaging. 2010 Feb;54(1):16-23.
3
Diffusion weighted MR imaging of pancreatic islet cell tumors.胰腺胰岛细胞瘤的弥散加权磁共振成像。
Eur J Nucl Med Mol Imaging. 2013 Jun;40(6):897-907. doi: 10.1007/s00259-013-2371-5. Epub 2013 Mar 5.
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Pancreatic neuroendocrine tumors.胰腺神经内分泌肿瘤
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One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States.“类癌”百年之后:美国35825例神经内分泌肿瘤的流行病学及预后因素
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Functional MRI evaluation of tumor response in patients with neuroendocrine hepatic metastasis treated with transcatheter arterial chemoembolization.经动脉化疗栓塞治疗的神经内分泌肝转移患者肿瘤反应的功能磁共振成像评估
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6
CT and MR imaging findings of endocrine tumor of the pancreas according to WHO classification.根据世界卫生组织分类标准的胰腺内分泌肿瘤的CT和MR成像表现。
Eur J Radiol. 2007 Jun;62(3):371-7. doi: 10.1016/j.ejrad.2007.02.036. Epub 2007 Apr 11.
7
Imaging of neuroendocrine tumours (CT/MR/US).神经内分泌肿瘤的影像学检查(CT/MR/US)
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Multi-detector row CT of pancreatic islet cell tumors.胰岛细胞瘤的多排螺旋CT检查
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