Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Jpn J Radiol. 2011 Feb;29(2):156-60. doi: 10.1007/s11604-010-0516-z. Epub 2011 Feb 27.
Arteriovenous (AV) shunts are relatively uncommon in the liver and usually associated with advanced hepatocellular carcinoma (HCC). In patients with massive AV shunts complicating advanced HCC, transarterial chemoinfusion therapy is not effective because chemotherapeutic agents go through the shunts and may cause systemic toxicity as well as decrease the chemotherapeutic effects against the tumor. We report two cases of successful transcatheter venous embolization of massive AV shunts complicating advanced HCC using the Amplatzer Vascular Plug for transarterial chemoinfusion therapy.
动静脉(AV)分流在肝脏中相对少见,通常与晚期肝细胞癌(HCC)有关。在伴有大量 AV 分流的晚期 HCC 患者中,经动脉化疗灌注治疗效果不佳,因为化疗药物通过分流可能会导致全身毒性,同时降低对肿瘤的化疗效果。我们报告了两例使用 Amplatzer 血管塞成功栓塞晚期 HCC 合并大量 AV 分流的病例,为经动脉化疗灌注治疗提供了支持。