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吞咽困难在评估苍白球内侧部刺激治疗帕金森病患者中的作用:病例报告。

Role of dysphagia in evaluating Parkinson patients for subthalamic nucleus stimulation: a case report.

机构信息

Neurological Rehabilitation Center Godeshoehe, Waldstrasse 2-10, 53177, Bonn, Germany.

出版信息

J Neural Transm (Vienna). 2011 Sep;118(9):1345-8. doi: 10.1007/s00702-011-0608-7. Epub 2011 Feb 27.

DOI:10.1007/s00702-011-0608-7
PMID:21359972
Abstract

In the selection of Parkinson patients for deep brain stimulation (DBS) of the subthalamic nucleus (STN) a risk-benefit-analysis is performed regarding symptoms that commonly improve and symptoms that may deteriorate. Speech is among the symptoms that may deteriorate. In contrast, the differential effects of STN-DBS on swallowing are less clear. Here, we present a Parkinson patient with dysphagia from concomitant oculo-pharyngeal muscle dystrophy successfully treated by STN-DBS. The role of dysphagia in evaluating Parkinson patients for STN-DBS is discussed.

摘要

在选择帕金森病患者进行深部脑刺激(DBS)治疗丘脑底核(STN)时,需要对常见改善的症状和可能恶化的症状进行风险效益分析。言语是可能恶化的症状之一。相比之下,STN-DBS 对吞咽的影响差异尚不明确。本文报道了 1 例因眼咽肌营养不良而伴发吞咽困难的帕金森病患者,通过 STN-DBS 治疗后吞咽困难得到改善。本文讨论了吞咽困难在评估帕金森病患者行 STN-DBS 治疗中的作用。

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引用本文的文献

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本文引用的文献

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Individual fiber anatomy of the subthalamic region revealed with diffusion tensor imaging: a concept to identify the deep brain stimulation target for tremor suppression.应用弥散张量成像显示的丘脑底核的个体纤维解剖结构:用于识别抑制震颤的深部脑刺激靶点的概念。
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Effects of subthalamic stimulation on speech of consecutive patients with Parkinson disease.连续帕金森病患者丘脑底核刺激对言语的影响。
Neurology. 2011 Jan 4;76(1):80-6. doi: 10.1212/WNL.0b013e318203e7d0. Epub 2010 Nov 10.
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Deep brain stimulation for Parkinson disease: an expert consensus and review of key issues.
帕金森病的脑深部电刺激:专家共识及关键问题综述
Arch Neurol. 2011 Feb;68(2):165. doi: 10.1001/archneurol.2010.260. Epub 2010 Oct 11.
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Speech and swallowing disorders in Parkinson disease.帕金森病中的言语和吞咽障碍。
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Subthalamic nucleus deep brain stimulation improves deglutition in Parkinson's disease.丘脑底核深部脑刺激改善帕金森病患者的吞咽功能。
Mov Disord. 2008 Apr 15;23(5):676-83. doi: 10.1002/mds.21891.
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