Wu Di, Li Ya-Nan, Wu Li-Jun, Gao Hui-Yuan
The Liaoning Provincial Public Security Office, Shenyang 110032, China.
Yao Xue Xue Bao. 2010 Nov;45(11):1398-401.
Three compounds were isolated from the extract of Taxus cuspidta Sibe et Zucc with the column chromatography on silica gel and preparative HPLC methods. Their structures were identified according to the physicochemical properties and spectral analysis, and they were identified as (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol (1), 2-deacetoxy-7beta, 9a, 10beta-trideacetyltaxinine J (2) and (3aS, 4aR, 6S, 8S, 8aS, 9R, 10R, 10aS)-benz[f]azulene-6, 8, 9, 10 (3H)-terol, 3a, 4, 4a, 5, 6, 7, 8, 8a, 9, 10-decahydro-10a-(1-hydroxyl-1-methylethyl)-1, 8a-dimethyl-5-methylene (3). Among them, compound 1 was a new compound, and compounds 2, 3 were two novel natural products.
采用硅胶柱色谱法和制备型高效液相色谱法，从东北红豆杉提取物中分离得到3种化合物。根据其理化性质和光谱分析对其结构进行鉴定，分别鉴定为（E）-1-甲氧基-2-O-（对香豆酰基）-肌醇（1）、2-脱乙酰基-7β，9a，10β-三去乙酰基紫杉宁J（2）和（3aS，4aR，6S，8S，8aS，9R，10R，10aS）-苯并[f]薁-6,8,9,10（3H）-四醇，3a,4,4a,5,6,7,8,8a,9,10-十氢-10a-（1-羟基-1-甲基乙基）-1,8a-二甲基-5-亚甲基（3）。其中，化合物1为新化合物，化合物2、3为2种新天然产物。
